On Thursday, April 12 an FDA advisory panel will discuss
whether or not to recommend that the FDA approve Merck & Co’s COX-2
inhibitor, Arcoxia (etoricoxib). The drug is manufactured by Merck, the
same company that made Vioxx, which was pulled from the market in the fall of
2004. Merck applied for approval to sell Arcoxia as a treatment for the
signs and symptoms of osteoarthritis .
Currently, the only COX-2 inhibitor remaining on the market
is Celebrex , made by Pfizer, Inc. These COX-2 inhibitors are all types of
NSAIDs. Over the counter types of NSAIDs include naproxen (sold as Aleve)
and ibuprofen. The difference between the prescription COX-2s and the OTC
NSAIDS (and the big selling point) is that the COX-2s have a lower risk of
bleeding ulcers and other GI complications than other NSAIDs. However,
studies have shown that the COX-2s have a higher risk of heart attack and
strokes. Vioxx and Bextra were both subsequently...
Dear Dr. Borigini, My father (72 years old) has Rheumatoid Arthritis in his hand. I would like to know if an artimplant spacer will work for his condition, or if should he try hyalgan before. He had a triple heart bypass about 4 years ago and he has being using Celebrex to control the pain. If your father suffers from rheumatoid arthritis, and his disease is active, then he would probably be a candidate for disease modifying medications—assuming there are no contraindications. Hand surgery for rheumatoid arthritis is a rather common occurrence, but it is usually done to correct deformities in patients whose disease is relatively under control, or to remove stubborn inflammatory tissue around a joint (synovectomy) or tendon to avoid damage to those areas. Hyalgan is used in osteoarthritis ; it is FDA approved for knees, not finger joints. Celebrex is used in both osteoarthritis and rheumatoid arthritis. You mention that your father had heart bypass surgery, and I am sure you are awa...
Generic Name: NAPROXEN SUSTAINED-RELEASE - ORAL Pronounced: (nah-PROX-en) Naproxen sodium Oral Uses
Naproxen is used to relieve pain from various conditions
such as headache, muscle aches, dental pain, menstrual cramps, or arthritis. It
is also used to reduce fever and relieve minor aches and pain due to the common
cold or flu. This medication is known as a nonsteroidal anti-inflammatory drug
(NSAID). It works by blocking your body's production of certain natural
substances that cause inflammation. This effect helps to decrease swelling,
pain, or fever.
If you are treating a chronic condition such as arthritis,
ask your doctor about non-drug treatments and/or using other medications to
treat your pain. See also Warning section.
Do not give this medication to a child younger than 12
years unless directed by a doctor.
How To Use Naproxen sodium Oral
Read all directions on the product package before taking
this medication. If you ...
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