Researchers at the Fisher Center for Alzheimer’s Disease Research at The Rockefeller University have published the results of their recent study, which showed that non-steroidal anti-inflammatory drugs (NSAIDs) reduced the effectiveness of selective serotonin reuptake inhibitor (SSRI) antidepressants.
NSAIDs include over-the-counter medications like ibuprofen, aspirin and naproxen as well as prescriptions drugs such as Celebrex, Daypro, diclofenac, etodolac, ketoprofen, meloxicam, Mobic, Naprosyn, Relafen, Toradol, Voltaren, etc.
You may be wondering what this study has to do with chronic pain. Antidepressants are sometimes prescribed as a treatment for chronic pain because they help increase serotonin, which is important for pain modulation. If NSAIDs prevent antidepressants from being effective for depression, they may also interfere with the ability of antidepressants to reduce pain. Study Design and Results Scientists first tested their theory on mice...
Generic Name: CELECOXIB - ORAL Pronounced: (sell-eh-COX-ib) Celebrex Oral Interactions
Your doctor or pharmacist may already be aware of any
possible drug interactions and may be monitoring you for them. Do not start,
stop, or change the dosage of any medicine before checking with them
This drug should not be used with the following medication
because very serious interactions may occur:
If you are currently using the medication listed above,
tell your doctor or pharmacist before starting celecoxib.
Before using this medication, tell your doctor or
pharmacist of all prescription and nonprescription products you may use,
anti-platelet drugs (e.g., cilostazol,
high blood pressure drugs (including ACE inhibitors such as
captopril, lisinopril and angiotensin II receptor blockers such as losartan,
oral bisphosphonates (e.g., alendronate)
December 28, 1992, marked a new era for Migraine sufferers with FDA approval of injectable Imitrex (sumatriptan). Imitrex was the first Migraine abortive triptan medication, a class of medications that many Migraineurs would come to call “miracle drugs.” Imitrex tablets were approved by the FDA in 1995. Since then, six more triptans have entered the market – Maxalt , Zomig , Amerge , Axert , Frova , and Relpax . Although triptans are a marked improvement over previous treatment options, many Migraineurs have not been fully satisfied with their results. Some do not achieve full relief from triptans, and the recurrence of Migraines within 24 hours of the first dose has been common. With the patents on sumatriptan nearing their expiration, both generics of the current forms – injections, tablets, and nasal spray – and other medications containing sumatriptan are now in development and testing. The results involving Trexima, one such medication that is a com...
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