I was reading through the MyRACentral News Page the other day and an article about Celebrex caught my eye. Celebrex is a non-steroidal anti-inflammatory (NSAID) in the COX-2 inhibitor family. A similar drug, Vioxx, manufactured by rival company Merck, was withdrawn from the market in September 2004 because of increased risk of serious blood clotting, heart attacks and strokes. Three months later the FDA asked Pfizer to voluntarily stop all direct-to-consumer advertising of Celebrex. A few months later, Pfizer also pulled its drug, Bextra, from the market in early 2005, because of a link to a serious skin disorder. Although Pfizer has not advertised, Celebrex has remained on the market because the FDA determined that the benefits of the drug outweigh the significant risks. I haven’t seen the new media or print ads yet, but I think the new spin on the risks that is discussed in the news article is interesting. Apparently, Pfizer begins the...
A couple of months back I wrote a post discussing the concerns I and many others have regarding the return of severe gastrointestinal side effects as a result of the increasing use of the so-called traditional anti-inflammatories. This is of course to be expected due to the fears so many patients have now of the sole COX-2 inhibitor remaining on the market in the United States-- Celebrex . Many of my patients are simply refusing to take Celebrex out of fear it "might kill me." The issue of whether the use of COX-2 inhibitors with low-dose aspirin is reasonable for patients at risk of cardiovascular events raised its weary head once more the last few weeks. This time, a provocative article appeared in the December 22, 2007 issue of the British medical journal "The Lancet." The author, a rheumatologist at Stanford University, feels that COX-2 inhibitors are preferable to traditional anti-inflammatories (such as Motrin and Voltaren ) in p...
Generic Name: NAPROXEN SUSTAINED-RELEASE - ORAL Pronounced: (nah-PROX-en) Naproxen sodium Oral Uses
Naproxen is used to relieve pain from various conditions
such as headache, muscle aches, dental pain, menstrual cramps, or arthritis. It
is also used to reduce fever and relieve minor aches and pain due to the common
cold or flu. This medication is known as a nonsteroidal anti-inflammatory drug
(NSAID). It works by blocking your body's production of certain natural
substances that cause inflammation. This effect helps to decrease swelling,
pain, or fever.
If you are treating a chronic condition such as arthritis,
ask your doctor about non-drug treatments and/or using other medications to
treat your pain. See also Warning section.
Do not give this medication to a child younger than 12
years unless directed by a doctor.
How To Use Naproxen sodium Oral
Read all directions on the product package before taking
this medication. If you ...
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