Researchers at the Fisher Center for Alzheimer’s Disease Research at The Rockefeller University have published the results of their recent study, which showed that non-steroidal anti-inflammatory drugs (NSAIDs) reduced the effectiveness of selective serotonin reuptake inhibitor (SSRI) antidepressants.
NSAIDs include over-the-counter medications like ibuprofen, aspirin and naproxen as well as prescriptions drugs such as Celebrex, Daypro, diclofenac, etodolac, ketoprofen, meloxicam, Mobic, Naprosyn, Relafen, Toradol, Voltaren, etc.
You may be wondering what this study has to do with chronic pain. Antidepressants are sometimes prescribed as a treatment for chronic pain because they help increase serotonin, which is important for pain modulation. If NSAIDs prevent antidepressants from being effective for depression, they may also interfere with the ability of antidepressants to reduce pain. Study Design and Results Scientists first tested their theory on mice...
Generic Name: CELECOXIB - ORAL Pronounced: (sell-eh-COX-ib) Celebrex Oral Interactions
Your doctor or pharmacist may already be aware of any
possible drug interactions and may be monitoring you for them. Do not start,
stop, or change the dosage of any medicine before checking with them
This drug should not be used with the following medication
because very serious interactions may occur:
If you are currently using the medication listed above,
tell your doctor or pharmacist before starting celecoxib.
Before using this medication, tell your doctor or
pharmacist of all prescription and nonprescription products you may use,
anti-platelet drugs (e.g., cilostazol,
high blood pressure drugs (including ACE inhibitors such as
captopril, lisinopril and angiotensin II receptor blockers such as losartan,
oral bisphosphonates (e.g., alendronate)
Generic Name: NAPROXEN SUSTAINED-RELEASE - ORAL Pronounced: (nah-PROX-en) Naproxen sodium Oral Uses
Naproxen is used to relieve pain from various conditions
such as headache, muscle aches, dental pain, menstrual cramps, or arthritis. It
is also used to reduce fever and relieve minor aches and pain due to the common
cold or flu. This medication is known as a nonsteroidal anti-inflammatory drug
(NSAID). It works by blocking your body's production of certain natural
substances that cause inflammation. This effect helps to decrease swelling,
pain, or fever.
If you are treating a chronic condition such as arthritis,
ask your doctor about non-drug treatments and/or using other medications to
treat your pain. See also Warning section.
Do not give this medication to a child younger than 12
years unless directed by a doctor.
How To Use Naproxen sodium Oral
Read all directions on the product package before taking
this medication. If you ...
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