I was on Enbrel for about two years about 8 years ago and most of my symptoms disappeared and I gained alot of strength. It worked effectively for 2 years then  I had flare ups. For the past  5 years I have been on rituximab, a biological medicction which is even better. This is administered through two doses of an infusion which takes  about  6 hours at a time two weeks apart as a hospital day care case. This leave me with a more or less  a pain-free period of up to a year. I have a flare up about once a year when I need to have a top up. I live in the UK with our glorious National health Service and this costs me nothing.