Your doctor is right :) Never give up! There are many options available to us, RAers. Partner with your rheumy to find your own "magic" drug. It is a very individual journey for all of us. There is absolutely no one in the world who knows your body like you do. Listen to it. You'll be amazed how well it communicates with you, if you give it a chance.  This site is amazing with people who go through all of this. I will be forever grateful for the advice given to me here. It is a great therapy when you needed it. I was experiencing a huge setback last year when Enbrel stopped working, but now I'm full of energy, hope of living a 'normal' life again. It does not come easy. It takes many changes, but all of them are worth pursuing. You should not change your expectations of quality of life as long as there is hope for good treatment. Good luck in finding one!   Ili