Can't be a TNF blocker as Enbrel sent me to the hospital with a stroke and neurilogial damage in 2009. Rutixan didn't work for me. Orencia has had me in remission for 18 months but liver enzymes continued to climb. Took me off MTX, then sulfasalazine, still continued to climb. Took me off Orencia two months ago and did a liver biopsy. Bioplsy came back perfect! After two months off Orencia liver enzymes are coming down. Still in high range but closer to normal, at least they are down to double digits now.
I have come out of remission hard and fast. Can't wait to start something to get me some relief. I know there have been several new biologicals approved in the last couple of years. Interested in hearing how they have been working and what side effects people have had. Sometimes I feel treating RA is like playing Russian Roulette!