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I've been on methotrexate for about 9 months, and haven't had any stomach problems at all. I take it on Saturdays with my largest meal of the day. After about 4 months, on mtx, my morning stiffness disappeared. You'll have to have regular lab tests and exams to monitor your kidney, liver function and lung function, but I would not hesitate to try it, if I were you. Good luck to you.

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