• Thrive With RA™ Thrive With RA™
    April 14, 2011
    Anyone Seronegative RA with family history of RA?
    Thrive With RA™ Thrive With RA™
    April 14, 2011

    How many that are Seronegative RA have a family history of RA?  I am fourth generation RA -- all from the same family line.  I'm curious if others are similar.

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FROM OUR EXPERTS

  • Brad
    Health Guide
    April 21, 2011
    Brad
    Health Guide
    April 14, 2011

    I am sero negative RA, both my great grandfathers we think had it as well, they were crippled up pretty bad, but had no real healthcare to speak of. My Rheumy told me his sero neg pts tend to have a more severe case and are harder to control than sero pos. Lucky us!!

     

    Brad

  • Lisa Emrich
    Health Guide
    April 21, 2011
    Lisa Emrich
    Health Guide
    April 14, 2011

    I am seronegative and had two greatgrandmothers who had RA.  A cousin of mine was just dx with RA last year (do not know if she's seroneg or not).  As far as I know, no others in the family have/had RA but there are a lot of other autoimmune diseases on one side of the family.


FROM OUR COMMUNITY

  • andrew April 21, 2011
    andrew
    April 14, 2011

    I have seronegative RA. No family history of RA but others with autoimmune problems including Hashimoto's (hypothyroidism), psoriasis, and ankylosing spondylitis. My doc tells me that autoimmune tends to run in families.

    Andrew

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  • wonderwoman April 15, 2011
    wonderwoman
    April 14, 2011

    I am third generation ra and sero negative, I don't know whether my mother and grandmother were sero negative or not

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  • Thrive With RA™ April 21, 2011
    Thrive With RA™
    April 14, 2011

    Thank you all for your comments thus far.  It amazes me that despite family history of RA in many cases, there has not been a definitive statement by the medical profession that RA is indeed genetic, only that it "may be" genetic.  I suppose that applies to those that have RA with no family history, but it seems a bit vague for a disease that affects 1.3 M Americans. 

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