I just returned from my Rheumatologist and my ALT liver enzymes are signifigantly higher than 3 months ago. The only change that I've done is I'm taking 3,000 mg of fish oil a day starting a week after my last blood test 3 months ago. At that time my GP recommended it for high triglicerides. Has anyone else had or heard of this? I know there is a new "drug" out called Lovaza, which is esentially concentrated fish oil and one of the warnings is elevated ALT. I'm taking Enbrel and wellbutrin and vicoprofin. Any thoughts? Thanks.
5/12/10 1:25pm
I did a quick search in Google and found a number of mentions of these liver enzymes increasing in connection with fish oil, so it's possible that the two may be related. I'd recommend you consult a licensed doctor of naturopathic medicine - they specialize in supplements and herbal remedies and often know more about their side effects and interactions with other drugs than your family doctor might. However, in the meantime, you may want to consider stopping the fish oil to see if that helps.
5/12/10 7:11pm
I did another quick checking Google and did find some mentions of elevated liver enzymes with Enbrel. I'd recommend you contact your rheumatologist to discuss the issue.
6/27/12 9:06am
I have RA and I'm on Humira and methotrexate. My liver enzymes were slightly elevated and my Rheumatologist lowered my dose of methotrexate a little and ordered another blood test, expecting the enzymes to drop. I also have been taking krill oil and now I'm thinking maybe that has something to do with it. Dr doesn't think so. Blood test in 2 weeks...
Important:
We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of Remedy Health Media. Remedy Health Media does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.
8 Tips for Coping with Lupus 
10 Ways Lupus Affects the Body 
Conditions That Mimic Rheumatoid Arthritis 
5 Tips for Exercising with Lupus
By Sparky22— Last Modified: 06/27/12, First Published: 05/11/10
Featuring Content From:
- About Us |
- Contact Us |
- Privacy Policy |
- Terms of Use |
- Security Policy |
- Advertising Policy |
- Advertise With Us
By using this service, you accept our Terms of Use. Please read them. The consumer health information on is for informational purposes only and is not a substitute for medical advice or treatment for any medical conditions. You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. Copyright © 2013 Remedy Health Media, LLC. All Rights Reserved.
Thanks Lene. I spoke with my GP today and he does not think it's the fish oil, but I'm stopping it. I have an appointment with him in about 4 weeks and will get another blood test just before that. He did mention he thought it could be Enbrel, which really surprised me. Has anyone had enzyme increase from Enbrel? Thanks for your help.