Monday, June 15, 2009 Chapisrican asks

Q: Can i still use Humira if left it outside/overnight at room temperature instead of refrigerator?

My treatment comes every month, 2 prefilled syringes in a box wich I have to administer every other week. After injecting myself with the first syringe I left the box outside with the second syringe at the kitchen table, I totally forget to put the box back, I found out the box on table the next morning. I put the box back on refrigerator, I need to know if I'll be able to administer the syringe after been outside (syringe in the box) at room temperature????

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Answers (5)
6/15/09 7:49am

No you cannot.  You can only leave it out for a  max of 30 minutes after that it becomes no good. you need to reorder it.

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1/13/10 4:21pm

According to my doctor, the 30 min limit is not correct.  In fact, when I first took Humira at my doctor's office, and they were walking me through it, they instructed me (and did so themselves at the time) to leave the Humira pen out of the fridge for  about 1 hour before you take it... so that it comes up to room temperature.  

 

I have been on Humira for about 1 year, and have left the pen out for about an hour before each dose.  The Humira is definitely NOT ruined - and is still completely effective. 

 

For what it's worth, my doctor said the Humira could be without refrigeration for up to a day (but make every effort to avoid doing this).  

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11/ 1/10 7:30am

MY PHARMACY SAID THAT HUMIRA WILL ACTUALLY BE OK FOR UP TO 24 HOURS AT 70º. I just took it after 8 hours of sitting out. I will post again if I die.

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7/ 8/09 9:46pm

If you read the accompaning pamplet, you will see that Humira CAN NOT be left out of the refrig. How unfortunate for you, but I can see how it could have happened. Bummer!

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7/21/09 3:46am

Just a thought. Once I made a mistake with my Enbrel and spilled it all over and was unable to salvage any of it. I called Enbrel. told them what I had done and they shipped my dose to my pharmacy free of charge to me. Then a friend of mine left my MTX in the car over night and I called my pharmacy and the pharmacy replaced it free of charged. Don't be afraid to ask for help. These meds are costly errors are bound to happen.

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4/28/12 9:17am

Humira storage on trips

I've been investigating Humira storage for long periods away from home.

I have used Lyan Packaging boxes and their cool packs designed for a temperature range of 2-8 degrees C and checking the temperature with a Maplin electronic thermometer.

My conclusion is that it is possible to store drugs within the permitted range of temperature for periods of up to 90 hours without re-cooling the cool packs.

The insulation thickness inside the Lyan box should be increased fom 25 to 50 mm. 9 or replaced by 35 mm. polyurethane foam. If practical the lid thickness  should also be increased but it is not essential. I used a 35 by 35 by 25 cm. box and two 1 litre cool packs frozen in the freezer. I als put in at least one warm 0.5 litre cool pack to keep the drugs above freezing point for the first hour or so after assembling the package.

It is necessary to be careful handling haf frozen packs as they produce sharp crystals that can pierce the plastic film of the pack if handled roughly.

Roger

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4/28/12 5:24pm

The 2-8 degree C range is a standard packaging specification. It is unlikely that the drug has just this specific temperature range requirement. It does not have a tighter temperature range or the 2-8 degree C would cause problems. It is likely that the range is somewhat wider.

My partner has used humira for 6 months with success. A doctor has stated her blood results are very close to normal. Her symptoms have been relieved. However today I discovered the humira had been always stored at 13.5 degrees C. At least three doses had been stored for 6 weeks at this temperature.

We have changed the storage arrangements now of course.

 

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By Chapisrican— Last Modified: 04/28/12, First Published: 06/15/09