Hand-foot syndrome (HFS), or Palmar-Plantar Erythrodysesthesia (PPE), is a side effect of some types of chemotherapy and other medicines used to treat breast cancer. Hand-foot syndrome is a skin reaction that occurs when a small amount of the medication leaks out of capillaries (small blood vessels), usually on the palms of the hands and soles of the feet. When the medication leaks out of the capillaries, it can damage the surrounding tissues. Hand-foot syndrome can be painful and can affect your daily living.
Symptoms of hand-foot syndrome include:
tingling, burning, or itching sensation
redness (resembling a sunburn)
In severe cases of hand-foot syndrome you may have:
cracked, flaking, or peeling skin
blisters, ulcers, or sores appearing on your skin
difficulty walking or using your hands
The following breast cancer medications can cause hand-foot syndrome:
Xeloda (chemical name: capecitabine)
Adrucil (chemical name: 5-f...
Definition Hand-foot-mouth disease is a relatively common infection viral infection that usually begins in the throat. A similar infection is herpangina . Alternative Names Coxsackievirus infection Causes, incidence, and risk factors Hand-foot-and-mouth disease (HFMD) is most commonly caused by coxsackievirus A16, a member of the enterovirus family. The disease is not spread from pets, but it can be spread by person to person. You may catch it if you come into direct contact with nose and throat discharges, saliva, fluid from blisters, or the stools of an infected person. You are most contagious the first week you have the disease. The time between infection and the development of symptoms is about 3 - 7 days. The most important risk factor is age. The infection occurs most often in children under age 10, but can be seen in adolescents and occasionally adults. The outbreaks occur most often in the summer and early fall.
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