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I also feel completely fatigued and completely wiped out most of the time. I could sleep all day, most of the time and just feel generally unwell. I am on Humera and Methotrexate and feel that it is these that are making me feel this way. I spoke to my Rheumatology Nurse about this and she said it's just something you have to learn to live with!! It's either severe pain or feeling unwell. What a choice!! I would also be interested in hearing if anyone else has this problem and what they do about it. At the moment my life is on hold because I don't feel well enough to do much. Sorry I couldn't help but at least I know I'm not the only one feeling like this. Let's hope someone out there has some advice that helps.