Chemical name: Methotrexate, also known as amethopterin
Brand names: Mexate, Folex, Rheumatrex
Class: Antimetabolite chemotherapy. Fluorouracil, Gemzar, and Xeloda are other antimetabolites.
How it works: Antimetabolites kill cancer cells by acting as false building blocks in a cancer cell's genes, causing the cancer cell to die as it gets ready to divide.
Uses: Methotrexate often is used in combination with other chemotherapy medicines to treat:
Dear Dr. Borigini, I have been living with RA for about 8 years, diagnosed at age 25. I have been taking methotrexate and having good... Read more »
When you think of rheumatoid arthritis, you might picture swollen joints, stiffness, pain, deformity, and a lifetime of medications and... Read more »
If you haven't heard about it already, there has been a lot of discussion in the media recently about a shortage of Methotrexate... Read more »
I talked a few months ago about moving from the oral form of Methotrexate (MTX) to a higher dose of the injectable form. As I reported... Read more »
This is a study to compare a combination of the experimental drug ACZ885 and methotrexate to a placebo in patients with active rheumatoid arthritis.... Read more »
New Zealand researchers say the way methotrexate currently is used to treat rheumatoid arthritis (RA) is not fast enough to control the onset of the... Read more »
Drugmaker Novartis is reporting that its generic unit Sandoz has voluntarily recalled 24 lots of methotrexate injection due to the presence of small... Read more »
This is a study to determine the safety and effectiveness of golimumab, alone or in combination with methotrexate (Trexall, Rheumatrex), compared to... Read more »
Scientists say long-term use of methotrexate--even up to a year--does not reduce relapse rates in children who have juvenile idiopathic arthritis. Read more »