Will Methotrexate Someone Weight Loss?

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Ask the Expert: Methotrexate Side Effects

Dear Dr. Borigini,

I have been living with RA for about 8 years, diagnosed at age 25. I have been taking methotrexate and having good results with this treatment. My frustration however, is two fold. I have been unable to lose weight or to lower my cholesterol despite diet and exercising regularly. Can methotrexate can cause these two side effects? Or can RA itself cause these side effects?

I am not aware of methotrexate causing difficulty with weight loss or abnormalities in cholesterol...
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