Tuesday, February 14, 2012

Stopping autoimmune diseases--before they start

(Science Daily) UPDATED 2009-03-24
Scientists say they may have found a way to track the start of autoimmune disease such as multiple sclerosis, rheumatoid arthritis, diabetes, and lupus. According to new research published in the American Journal of Pathology, the molecule NF-κB is activated by inflammation, which plays a key role in autoimmune disease development. This makes NF-κB a prime candidate to track autoimmune activity, researchers say. Now scientists have engineered this molecule in mice so that it emits light when it is activated by inflammation. This makes the molecule visible before disease symptoms actually appear. Investigators say this advance will make it easier for them to see when autoimmune diseases are beginning to develop, which could lead to possible preventions or cures.  Read full story >
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