Tuesday, February 9, 2010
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FDA panel recommends lower doses for acetaminophen

(NPR) UPDATED 2009-06-30
An expert panel that advises the U.S. Food and Drug Administration (FDA) says the maximum dose for pain medications that contain acetaminophen should be reduced to help curb deadly overdoses among users. Acetaminophen is one of the most widely used drugs in the United States, the key ingredient in such painkillers as Tylenol and Excedrin. But FDA officials say it's also the leading cause of liver failure, sending 56,000 people to U.S. emergency rooms every year. In a series of votes today, the FDA's expert panel advised lowering the maximum single dose of the drug from 1,000 mg to 650 mg. The panel said the 1,000 mg dose should only be available by prescription. The FDA is not required to follow the recommendations of its expert panels, but it usually does.  Read full story >
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