I read the same story and I too had the same question that you did. But after reading Christina's reply then I came to the same conclusion she did. I have been taking 600 milligrams of Seroquel for around 2.5 years and feel I am the most stable I have been in years. For me Seroquel is working wonders. I may bring up the study when I see my psychiatrist in March but I feel that I also am the healthiest I have been in years. In a little over 2.5 years I have brought my weight down from 200 pounds to 140 and also like Christina's grandmother my parents are living and are now 84 and 80 years old. At first the study had me somewhat concerned but then I came to realize almost all drugs have some sort of side effects and yes this one is serious but I do have confidence in my psychiatrist and feel if I start to have any health issues we will work together as a team to come up with the right medication and proper dosage.