Is there any scientic reason while a medication a person is on stops working without any warning?

Janet:

I think you'll have to talk to your psychiatrist about this.

I can tell you this: I took the same medication for over 40 years.  It worked perfectly.  And then one day it just stopped working (right in the middle of a speech I was giving).  When the program was opened for questions I found I didn't understand anything and everything that I was asked.  It was like falling of a cliff.  It has taken my psychiatrist and I approximately three years to find a new cocktail of meds that works for me.  During this period I experienced psuedo-parkinson's symptoms, problems with cognition, excess sedation, anxiety and depression.  It was a bummer.  It was suggested to me that the problem might have been caused as a consequence of the normal aging process, that my brain psysiology might have undergoing changes that rendered the medicine ineffective.  I really don't they know. 

Robin

Hello Janet,

I wondered that, too, and I'm going to ask my psychiatrist tomorrow when I see him.  Last week I "researched myself" and the events going on in my life when the Stelazine started to lose effectiveness.  I wondered if there was a cause-and-effect relationship.  Though Dr.  Altman did tell me, when I had the meltdown last year, "The drug has run its course."  So perhaps it was a miracle I found symptom relief for close to 21 years with one medication.

Again, as Robin said, your psychiatrist should be in a better position answer the question.

Regards,

Chri

This is known with ssri's.  I'm not sure about the other classes of drugs.

This is known with ssri's.  I'm not sure about the other classes of drugs.

I guess after you've hit certain receptors for so long they become unresponsive.