My mother, 89-year-old, (a medical doctor in her past) is permanently living in Assisted Care home from 2006. She has Dementia. Once, 6-7 years ago, she was diagnosed as having paranoia and SZ. I do not believe she has Schitzophrenia (no history, no events), but I believe that she has been having Paranoia for many years, may be even from her childhood.

Recently, she started having outbursts of anger which, as I heard, are the signs of advanced Denentia. When she was hospitalized recently, due to some orthopedic problem, and was later transferred to Rehab, she had very severe epizodes of aggression, in both places, especially when some blood had to be drawn, or some shuts given, or even when some pills were offered to swallow. Because she was becoming very aggressive and even physical, she was given Seroquel, daily doze 75 mg. She's been on this drug since October' 08. (She is also on Paxil and on Aricept (5 mg.)

In December'07, she was back to her Assisted Living facility. Because she was behaving well, a week ago her current doctor decided to increase her Aricept to 10 mg and start gradually decreasing Seroquel from 75 to 50 mg. All of a sudden, she became very disagreeable, stubborn and suspicious, and do not let nurses giving her drugs or B12 shots. I think that Seroquel also "cured" her paranoia a little. However, taking this drug, she developed some tremor and began loosing her hair. Can you please suggest what would be the best treatment (drug) for her age - to keep paranoia under control but not  damage her physical health? I know that FDA banished a group of some psychotropic drugs for the seniors. What would you suggest - to keep her  behavior balanced?