Hello handslewis,   I hope your mother is able to find some peace of mind, and taking psychotropic medication could possibly help her delusions.  The atypicals used in the U.S. are Quetiapine (Seroquel), Risperidone (Risperdal), Olanzapine (Zyprexa) Aripiprazole (Abilify), Ziprasidone (Geodon) and Clozapine (Clozaril).   I'm surprised your mother's doctor hasn't tried her on any of these, if her diagnosis is schizophrenia, or maybe she's not taking her meds.  Sometimes, the longer a person goes without medication, it's harder for the medication to alleviate the symptoms once he or she is placed on medication.  In mid-Decmeber, after my Working Life blog series is finished, I'll be quoting information from the November 2008 Hard Mental Health Letter which talks about the benefits of early intervention.   So, if your mother is taking her meds and they're not working, she should still take them and work with the doctor to find the appropriate meds that alleviate her symptoms and her pain.  As I've suggested, she has a number of medications to choose from.   If at all your mother has anosognosia, the lack of awareness that she has an illness, I suggest you read Xavier Amador's book, I Am Not Sick, I Don't Need Help which couches family members on what to say and how to say it when you try to influence a loved one to get and stay in treatment.  A person doesn't have to believe she's sick to be able to take meds, she just has to perceive that taking them will enable her to achieve a life goal.  And if your mother commits to staying clean, she can have a good life.  And if she's on the path to staying clean, she's probably in a good enough place where you can devlop a relationship of trust with her, and use some of the techniques outlined in Amador's book to help her get treatment.   I wish you and your mother some comfort now.   Regards, Christina