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It is not uncommon for women to develop sz during their late 30's.  I was diagnosed at 37, but I had had depression and mild symptoms of sz for years.  Up until that time, it just had not been severe enough to impact my ability to work or sustain a relationship.  Then suddenly my mental health was severely compromised and the sz was so serious I had to be hospitalized over and over again.  I think I could have avoided some of that if I had taken the prescribed medications.  But, as sick as I was, I would take the meds just enough to feel better, then I assumed I didn't need them anymore.  Wrong!  Encourage your sister to find a good psychiatrist and to be committed to a treatment plan.  You might also tell her about this web site -- the people are great here.   Carolyn