I am an active 28 year old female. I have a history of depression and anxiety but have only been receiving treatment for about a year and a half. My psychiatrist has me go in for routine blood tests and my most recent test indicated that my vitamin D was low (20 ng/ml). I thought it was strange that it was low because I had been getting a lot of sunshine in recent months (I was training for a 5K and was running outdoors 30 min to 1 hr every 1-2 days), and I've always had at least one glass of milk or yogurt every day. Apparently my vitamin D was also low the previous year as well but they forgot to tell me (gotta love the health care system...). My psychiatrist had me begin taking vitamin D supplements (800 IU/day) and within a couple of weeks I started feeling awful. It started with an upset stomach and minor nausea, a bit of dizziness and shortness of breath, as well as extreme fatigue and sleepiness. I am usually tired a lot anyway, but this was worse than usual. Sometimes I would just get so tired I would have to stop whatever I was doing and take a nap. It was hard to concentrate on anything at work and I kept forgetting even the simplest things. Next my GERD starting acting up and I just felt achy all over in addition to sharp shooting pains in random places that I believe was either bone or nerve pain (definitely not muscle pain) mostly in my ribs, back, arms, and lower legs. I went to see my doctor and asked him if my calcium was high and if I should have had it tested before taking the vitamin D. He said it had been tested and was normal (10 mg/dL, surprise! I am starting to think my HCP has some communication issues...). He told me to stop the vitamin D....I should feel better within 3-5 days and check in with him in 2 weeks for good measure. However, I didn't feel better. In fact, almost 2 weeks later, I feel 10x worse. The GERD is getting to be unbearable. I started to have pain in my shins that hurt bad enough that I had to stop my running routine. I think the shin pain may have actually started before starting the vitamin D, but then it only hurt when I was running. I thought it would get better if I stopped running but it only got worse. Its definitely not muscle pain. I think its in my bones. After perusing some medical journals...(I should say that I do have a background in the biological sciences, though my specialty is in genetics and DNA metabolism)...to me these symptoms seem to be consistent with hypercalcemia. What worries me is that the symptoms are not entirely new. All of them have appeared (seemingly randomly) every now and then over the last 5-10 years, but never to this severity. In the past the symptoms often came with waves of depression and anxiety and (I think, and even thought then) that they were erroneously attributed to my psychological state. But this time I am not depressed or anxious thanks to my daily Zoloft which I didn't have before. So I ask, could I have a high basal level of blood calcium that through feedback mechanisms keeps my vitamin D low to limit absorption of more calcium into bloodstream? What would cause something like this to happen? Could this be why I tend to be tired a lot or am prone to waves of depression? What types of tests or treatments should I ask my doctor about when I go to see him next? Finally, If I do have a mineral imbalance could it be linked to my dental condition. I have amelogenesis imperfecta (hypocalcification of the enamel layer of my teeth) that has affected most of my primary teeth and a few of my adult teeth. I also have thin, brittle toe and fingernails that occasionally get white spots on them. I have long wondered whether this was related to my dental condition as well. I am starting to think all of this is related. But maybe I am just crazy! Sorry for the long-winded discussion but I felt I needed to get down all of the relevent information.