Hi Ven,

I understand your concern that your sister get total relief from her symptoms.

I do not ordinarily sing the praises of any drug as the best one to treat schizophrenia.

That is because each person's chemistry responds differently to different drugs.

For example, I take Geodon and have virtually no symptoms and absolutely no side effects from the drug, yet another person on Geodon has excessive sleepiness that disrupts his ability to have a daily work routine.  When I say I have no symptoms, I mean I have none of the positive symptoms I had when I was diagnosed in 1987, and I have no negative symptoms, either.

If you heard that two of the drugs you listed shouldn't be taken together, I would have your sister bring this up to the psychiatrist.

In the end, there's no objective criteria for saying one other medicine would be equivalent to clozapine because, like I said, each drug has a different effect on different people.  My experience with the Geodon was that it is a miracle drug for me.

You do not say if the combo of the three new drugs ISN'T working for your sister as well as the clozapine did, yet I believe that could be what you're inferring, otherwise you wouldn't have a concern about those drugs, right?

With any new drug routine, you have to give it time for the drug to work.  If, after a reasonable tenure with that one drug no relief has been found, the psychiatrist should try every other drug or combination of drugs, or every new drug that comes out on the market, until relief IS found.

I hope this helps.

Regards,

Christina