Hello David,   Your experience with the Seroquel is the first of its kind I've heard from someone taking this drug.  It's your call.  If the thoughts are troubling you, go back to the psychiatrist and work with him or her to find the drug that will have minimal side effects yet give you relief from the troubling thoughts.  Seroquel isn't the only drug used to treat SZ and related conditions, there are a variety and for example I'm on an atypical that has caused me to be even more focused than I already was, I can think clearly now.   If you find after going off the Seroquel that you can't control your thoughts or cope with what's going on in your head, do consider working with the doctor to find relief via another drug.  I am a writer and as you'll see from reading my SharePosts, I have a sunny outlook, so each person is different and you have to know your comfort level with referencing death and mortality.  You say it frightened you so obviously you were concerned with the frequency or severity of the thoughts, and that's the key: if you can live with them or are they interfering with your life.  Years later you did take the Seroquel so at the time you took the drug you felt the thoughts had gotten worse or you couldn't control them any longer, right?   As I said, it's your call whether you take the drug or not.  I do not feel the lack of motivation would be long-term.  I sure hope the lack of motivation doesn't continue.   Regards, Christina