Seroquel Oral

Seroquel Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

• sibutramine

If you are currently using this medication, tell your doctor or pharmacist before starting quetiapine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• anticholinergics (e.g., belladonna alkaloids, benztropine, scopolamine)
• dopamine-like drugs (e.g., bromocriptine, cabergoline)
• levodopa
• rifabutin
• drugs for treating high blood pressure (e.g., alpha blockers such as prazosin, calcium channel blockers such as diltiazem, "water pills"/diuretics such as hydrochlorothiazide)
• drugs affecting liver enzymes that remove quetiapine from your body (e.g., azole antifungals such as fluconazole/ketoconazole/itraconazole, barbiturates such as phenobarbital, glucocorticoids such as dexamethasone, macrolide antibiotics such as erythromycin, rifampin, certain anti-seizure drugs such as carbamazepine/phenytoin, thioridazine)
• thyroid medicine (e.g., thyroxine)

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with quetiapine such as: bupropion, isoniazid (INH), other antipsychotics (e.g., chlorpromazine), tramadol, theophylline, and tricyclic antidepressants (e.g., amitriptyline), among others. Consult your doctor or pharmacist for details.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.