I have recently been diagnosed with simple and complex endometreial hyperplasia and just started progesterone therapy today.
Had CA-125 bloodtest done (I asked for it) and it came back at 44. My gyno said she considers anything under 100 normal. I am now unsure.
Thanks
Hello Deetee
I can imagine this must be a scary time of being tested. What sorts of tests did you have done?
I would trust your doctor. Did she give you any information about your condition or what your risks are?
I am not a doctor but I imagine that she did the CA-125 blood test to make sure that you do not have cancer.
Here is some information about endometrial hyperplasia from The American College of Obstetricians and Gynecologists:
"Endometrial hyperplasia is a condition that occurs when the lining of the uterus (endometrium) grows too much. It is a benign (not cancer) condition. In some cases, however, it can lead to cancer of the uterus."
And here is information about the CA-125 bloodtest:
"CA 125 is a substance released into the bloodstream by many, but not all, endometrial and ovarian cancers. Very high blood CA 125 levels suggest that an endometrial cancer has probably spread beyond the uterus. Some doctors will use this in deciding whether surgery should be done by a gynecologic oncologist. If CA 125 levels are high before surgery, some doctors use follow-up measurements to find out how well the treatment is working (levels will drop after surgery if treatment is effective) and to see if the cancer has come back after initially successful treatment."
So this test was done to ensure that you do not have cancer but I am sure they also must have done other tests as well correct?
I would call your doctor and address any concerns you have directly with her.
Thank you for your question.
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Hi;
I have the hyperplasia without atypia (which is a good thing). If you have atypia, I believe it's pre-cancerous. My doctor wasn't keen on the test but I was the one who asked for it. I recently had a transvaginal ultrasound done and the only thing they found was a tiny cyst measuring 2cm.
She told me right out that anything under 100 is fine (like I mentioned). The only thing I do know for sure is about the hyperplasia w/out atypia. I am not scared, I just don't want to have to get my uterus removed ... if this form of treatment doesn't work! Then again ... no periods!!!! I have 3 children already and we are good with that! It's having surgery that bugs me.
She also said my condition has a 3% chance of turning to cancer if NO treatment is done. Turning that around .. that's a 97% chance it won't!
I know my mom's doctor stopped doing that bloodtest on her because it isn't reliable, especially if you use it without any other measure (ie: ultrasound) and if you haven't gone through menopause (which I haven't yet).
Thanks for your information.
deetee