I don't think there is anyone here qualified to make that judgment. Here is some information on Premarin (I assume that's what you meant) from Drugs.com. You can read that. It mentions not using it to treat heart disease because it may increase the risk of developing these conditions, but it doesn't say what those might be.
I wish I could help you find the information, but there may not have studies on this. I just don't know. Maybe someone else will, yet.
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