Progressive Multifocal Leukoencephalopathy

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Definition

Progressive multifocal leukoencephalopathy (PML) is a rare disorder that damages the material (myelin) that covers and protects nerves in the white matter of the brain.


Alternative Names

PML


Causes, incidence, and risk factors

The JC virus (JCV) causes PML. By age 10, most people have been infected with this virus, but it hardly ever causes symptoms.

Anyone with a weakened immune system, however, are at greater risk of developing PML. Causes of a weakened immune system include:

  • AIDS (less...
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