Saturday, June 02, 2012

Efudex, Aldara and Other Skin Cancer Topical Chemo Creams

By Kevin Berman, MD, PhD, Health Guide Monday, March 19, 2007
Hi everyone.  Today I want to talk about the two topical therapies used to treat certain pre-cancerous lesions and early superficial skin cancers.  The two creams are 5-fluorouracil (trade names efudex and carac) and imiquimod (trade name aldara).  First, let's talk about these...
Mohs Surgery: What Will the Scars Look Like?
Anonymous
Anonymous
3/21/07 1:44am
Had a slow growing stickey skin cancer for 10+years on chest.  Half-dollar sized.  Freeze, Efudex, surgery=no cure and no change.  Finally an Aldera course.  Now, 4 years later, still no spot.
4/ 1/07 12:51pm
Does someone have an answer?   Is it OK to use makeup and sunscreen lotion when you go out while you are using aldara 2 nights a week for 4 months?
I'd appreciate any info you might have.
Anonymous
Anonymous
2/10/09 6:37pm

Yes, it is recommended to use suncreen while using aldara at all times.  My derm also discussed with me  the ease of using makeup to coverup lesions from aldara as opposed to effudex,  which causes scabbing.

Anonymous
Esra
5/25/07 9:15pm

Dr Berman,


I have just been diagnosed with above in the vulva. I have been given Aldara to use for the next 2 months. Have done some research and found some terrifying information as well as good. There is a website Aldara1.com which 3M tried to take down but lost. Also 3M Pharmaceuticals settle a lawsuit outside of courts for a man who got extremely sick. Please advise how come Aldara is being prescribed? If this is true how can doctors play russian rullet with the public? Please help

Anonymous
glad to serve
7/24/08 1:27pm
I was talking to the various pharmaceutical companies and I learned that once a drug is FDA approved a doctor can use it for anything he/she chooses to prescribe it for. I too am suffering greatly from misapplication of a drug. Efudex is labled specifically not for intravaginal use. My doctor said "trust me, I know what I am doing". Six months later, suffering from chemical vaginitis and chemically induced cystitis as confirmed by cystoscope I asked my gynocologist if they still stood by "trust me". I was told that the urologist has a right to his opinion but the gynocologist still feels it is perfectly safe. I wish I could trade bodies with that doctor for one day, so they could experience what they are so coldly dismissing. This is extremely painful, unnecessary and has put the breaks on all of my personal plans since February.
Anonymous
Anonymous
8/ 8/09 1:03pm

I don't think it is Russian roulette.. everybody is different in how they react to the treatment..I used Aldera for 4 months ,I must admit it wasn't the nicest experience I have ever had but It looks like now that the black scabs have all gone all my skin has to to is heal from the redness from being raw. I am happy that that part is over with now I have to deal with my nose  and hopefully same thing will happen and I can get back to being me again,also the vulva is a much more sensitive area just dab small amount on

Skin cancer is as my derm said from a lack of using sunscreens and basking in the sun or using the tanning salons.As I told him when we were young it was baby oil and iodine and that basically cooked our skin~~even after so many terrible burns it took me until my late 20's early 30's to smarten up, although I used it for my kids I never put it on religiously....The derms do as much as as best the can to treat everyone and hopefully help them with thier problem I hope this helps you~~~if you have aldera USE it I am not sorry at all and I didn't have much problems ohhh maybe a tiny bit of hair loss but that I think was because I was on it for so long it is basically a chem tratment by cream..Good Luck!

Anonymous
Anonymous
6/26/07 6:11pm
Have been treating my face and chest for3+ weeks 2x's week with Aldara. Have large open oozing sores, diahreah for 3 weeks and horrific flu like symptoms for 2 days after each treatment..pins and needle feeling throughout my body, joint and muscle aches with slight fever. I have been megadosing vitamin c thinking I was getting a flu. Curios about these symptoms I researched Aldara on line and was horrified to read how dangerous it can be. Many people including physicians are trying to get this off the market.
Anonymous
Anonymous
9/10/08 11:36pm

I have treated literally hundreds of squamous cell in situ skin cancers and actinic keratosis with Aldara with great success.  There are a very few people who will have severe reactions to using Aldara topically, but generally when someone has a severe systemic reaction this happens for one of two reasons. 1. They apply the entire package of Aldara to a single small skin lesion when with most small lesions a single packet contains enough medicine for 8-12 applications. Just take a bit of tape and close up the packet to save the remainder until time for the next treatment. (2) People can have a severe reaction if they get any Aldara on a mucous membrane or inside the edge of their nose or in their eye. In this situation Aldara can rarely cause flulike symptoms caused by a cytokine cascade creating temporary high levels of interferons, ILs and NKCells that causes the flulike symptoms. This can be a little scary but unless you stick an entire packet up your nose you will quickly recover. Some tylenol or ibuprofen will make you feel better if this should happen to you. Also call your Dr.

 

I think Aldara is a miracle drug compared to having to get repeated excisions of skin cancers. I also like being able to tell if a lesion is probably malignant due to the reaction created by applying Aldara. If there is no reaction then the lesion is not likely to be skin cancer but something else. Then you need a biopsy to find out what is going on. In my personal experience Aldara works better on SCC than on BCC. There is a learning curve to figuring out how best to use Aldara and I am sure there arer plenty of Drs who do a poor job of telling the patient what to expect, but once you figure out how to properly use this medicine it can save you a lot of cutting and scars plus you can treat small lesions as soon as you suspect a skin cancer rather than having to wait for an excision and the pathologist report.

Anonymous
Stephen
9/24/09 10:29pm

Dear Anonymous,

Your description of Aldara is perfect.  I had Mohs surgery on my scalp for a squamous cell in situ.  After the Mohs surgury I used Aldara for some actinic keratosis.  The first four weeks nothing after five weeks the Aldara started to work. The last weeks of my Aldara treatment were rough but three weeks after I finished my treatments my skin was smooth and clear.  I am confident I could have beaten the squamous cell in situ skin cancer without the Mohs surgery but the Aldara was not mentioned.  To anyone with a skin problem go on the internet and learn about your problem and choices and talk to your doctor.  I wish I did research before any choice.

2/10/11 5:18pm

I was told to use Effudex on my squamous cell cancer on my face.  At first my dermatologist said to go to a Moh's specialist, then when I went back to have him specify the exact location of the cancer he had removed by a biopsy (very small rough spot on nose and cheek).  He then said, it was so small and to just do Effudex for 4 weeks.  Do you regret the Moh's?  Can Effudex be used on Squamous and be effective or should I do the Moh's to be sure it is gone?

Anonymous
Stephen
2/10/11 10:12pm

I'm not a doctor I can only give you my opion and my story.  The biopsy removed the squamous cell carinoma in situ that I had.  When I went for the

Mohs surgery he couldn't find anything and took a bit more skin and still did not find anything.  It is not uncommon that the biopsy can remove the bad cell if

you catch it soon enough.  I like using the Aldara on Actinic Keratosis and believe it would work on the squamous cell carinoma in situ.  I was given a new product that I like the best "Zyclara".  It's similar to the Aldara but easier for

me.  If you need me to email you a picture of what it looks like when it working,

let me know.  It's important to understand that all of the topical creams work

a little different for everyone.  I know I have Actinic Keratosis and I am dertermined to fight them.  If you decide to use any of the creams and it gets ugly it means its working.  I tried Carac in the begining of my fight with no reaction.  What every you choose the Dermatologist can give you some Bionect cream which helps with the healing when you finish. 

 

   

Anonymous
Frisky
3/27/11 12:52pm

Do the mohls. I have had 6-7 over 20 years and all but one did not come back.

Anonymous
LMA
8/23/07 1:31am
I am starting this treatment soon for vaginal pre-cancer.  Any tips.  I am scared of the pain i have been warned about.
Anonymous
Robyn N.
9/20/07 9:52pm
It is a horrendous treatment. I went hrough six treatments before having to stop, pain, nausea, burning. First get a second opinion from a gyno-oncologist. My second opinion oncologist said he has not used this drug for 15 years, that the treatment was way worse than any cancer. Stop, run and seek a second opinion.
Anonymous
Linda
12/ 8/07 9:59pm
Just the opposite for me.  Absolutely no problems.  I read on another website to use petroleum jelly on the outside skin area in case of any burning.  Very very rarely did I feel burning, and when I did, I used the jelly and had absolutely NO problems.  I was scared to death to use it after reading all the "stories" on the Internet, only to find out I had absolutely nothing to fear
Anonymous
Marlena
12/29/07 3:06pm

I just began it last night and am very glad to see your note here.  Thanks and it gives me hope that I won't come out of this horrified.

 

Anonymous
Marlena
1/ 6/08 10:08am
Update: I completed my 7 days of therapy.  Used Zinc Oxide on outside and no burning but the damage on the inside is horrendous.  Since stopping, my vaginal opening is sealing up. Nothing is stopping it.  It is painful to reopen.  Bath after bath to give myself relief from dryness and pain.  I don't want to do the next treatment.  I am scared to death.  I don't know what the final healing from this course of treatment will be.  Any pointers from anyone on relief or how to stop this closure from happening?
Anonymous
Janice
1/18/08 7:33pm

I went through this nine years ago. The pain is no fun. I used the petroleum jelly even around the opening.  The best way I found to insert the applicator with all the raw flesh is that I put just a little bit of lubricant on the tip  of the applicator, put one foot up on the toilet seat and inserted it as fast as I could. 

 

After all is said and done, it wasn't fun but I have not had one irregular pap since, and I battled cancer for years, had a hysterectomy, went through interferon injections, laser and I finally got relief after this treatment.

Anonymous
glad to serve
7/24/08 1:16pm

Efudex is a dangerous product with serious complications.  http://www.getoomph.com/pdfs/EfudexPatientBrochure.pdf Read page three of this link and you will see that the company warns against intravaginal use due to vaginal necrosis, ulcerarations, and other local reactions.  I can personally tell you that it does not target bad cells.  It affects and kills every cell that it comes in contact with.  I can see where it is entirely capable of sealing off a vaginal opening.  The best thing you can do is keep vaseline or neosporin on the affected area.  Once all the tissue is killed off, the body's natural healing process will seal together raw tissue.  I personally underwent this treatment without a full understanding of how much damage it would do.  It caused me to suffer from intense pain and swelling due chemical vaginitis.  I also have suffered from chemically induced cystitis according to the cystoscope performed by my Urologist.  EVERYONE should know that this drug is so dangerous that the FDA gave it their Box Warning:High Alert Medication: "The Institute for Safe Medication Practices includes this medication among its list of drugs which have a heightened risk of causing significant patient harm when used in error."  This is copied from the Merck Manual website. This drug is supposed to administered as a last option and only by a physician trained in the safe use of this drug. I began treatment intravaginally in February and I am still suffering greatly.  Never trust a doctor who tells ou that even though the box says specifically NOT FOR INTRAVAGINAL USE, that they know what they are doing and it is perfectly safe.  It is not safe!  That is why all these warnings are posted on the internet.  Click on this link to find out about studies on the success rate of this treatment.  The study shows that folks on placebo had a higher recovery rate than those on Efudex intravaginally.  Why?  Most likely the weakened tissue was more susceptble to dysplasia/virus cells.   http://www.hindawi.com/getarticle.aspx?doi=10.1155/s1064744999000319     

Anonymous
Anonymous
10/27/08 6:22pm

I am in week 4 of efudex treatment for vaginal dysplasia and, like you, have had no problems.  Did you apply petroleum jelly before insertion of the cream or after or just when you had any burning.  If I get a tinge of burning upon urination, find that if I drink lots of water I do not have it.  Just curious if you are still having normal colposcopies or have any problems recurred?

Anonymous
Anonymous
11/ 6/08 10:16am

I used efudex a few months ago with no results--good or bad. But wanted suggest that if you have a tight or narrow vagina, you might want to ask your MD about using a vaginal dialator. My vagina was extremely tight (due in part, and most unfortunately, to lack of use) which resulted in very painful gyn exams. So finally my gyn/oncolgy MD gave me an extra small and a small vaginal dialator. Having worked my way up to the small size, I now find that the use of the small speculum is no longer painful (never mind the biopsies and other insults to my integrity). I hope that this will be of help.

Lisa

9/ 9/07 8:39pm
I am on day 10 of 2X day Carac Cream for AK's on my face.  Not a terrible reaction yet.  I hear that the third week is the worse.  What is the difference between Effudex and Carac??
3/21/08 9:02pm

Jimbo61,

 

Im on 9th day of Carac tonight.  I wanted to get on your site of talk to you here because I tried to get on you skin journey site and it would not let me.  I hope you reply.. I have questions.

3/21/08 9:22pm

Hi Rhonda,

Sorry I took my site down to work on other issues.  I would be more than happy to answer any questions you may have.  My email is Jfoster1961@msn.com

My best,

Jim 

Anonymous
Amanda
1/18/08 10:20am
I've been on the treatment for about two weeks now, taking it 3 times a week. For the past week, I've woken up with insane itching around three or four in the morning every morning. It's getting to the point where I'm having trouble going to the bathroom and for the life of me can't ignore the problems this is causing me. I can deal with a lot, but it's beginning to be very bothersome. Anything I can use to help the pain/itching? I tried to call my doctor this morning, but after three failed attempts and the fact that I can't afford a doctor's visit [thanks to having no insurance!] I'm not sure what else to do.
Anonymous
Amanda
1/18/08 10:21am
Sorry, I didn't make it clear that I was using the Aldara cream.
Anonymous
ted
1/21/08 4:47pm
hang in there, Ive just been through the same symptoms, I found that dehydration is a problem, causing the itching, take plenty of fluids and 2 neurofen before bed, also heaps and heaps of moisturiser after you finish the efudex treatment
Anonymous
Anonymous
9/10/08 11:40pm

Have your Dr prescribe you some 5% Lidocaine ointment and then alternate using the Lidocaine ointment a few hours before or after using the Aldara. This will take care of the pain.

Anonymous
laura holt
2/ 7/08 9:35pm
I am currently using aldara and it is not easy. It is painful after 3 weeks of using it 5 days a week. the areas on my face where I am applying it look horrible, and I have to work everyday,it is difficult, really hard. I have had skin cancer for over 20 years and I am 47. I have used effudex, have had mohs surgery. It is really difficult, but I keep thinking I will be done with this soon and then I will look normal for a while. I realize many people have many serious health issues, but sometimes this really gets me down. Please everyone, just try to get through every day.
Anonymous
Rebecca
2/10/08 11:42am
Laura -  I hope your weeks of treatment go fast for you.  I am facing the decision of either doing Mohs or Aldara for a bcc on the side of my nose.  If it weren't in the middle of my face it would be easy to pick surgery and just have a scar somewhere.  But because it would be in such an obvious place, I am thinking that maybe I should try to live though the Aldara for 8 weeks and not have to live with a scar for the rest of my life.  Why if you have done surgery in the past did you pick Aldara this time?  Do you regret it?  Am I going to better off with just doing the surgery?  Any advise would be appreciated!    Reb
Anonymous
upc
6/14/08 12:28am

I began aldara three weeks ago, I have taken breaks during that time when I did not use it, and now I have stopped forever.  I had a tiny cancer on my  chest so small that even the dermatologists really didn't know where it was.  But I really didn't want the surgery, so thought that using aldara was the perfect answer.  Now I am so sorry that I let anyone do anything, my whole upper chest is a mass of open sores, I'm putting neoporesporin on it, I have to cover it during the day, it bleeds and sticks to my shirt, I leave it exposed at night, but it doesn't seem to be healing.  I'm 76 years old, have arthritis, but am otherwise healthy.  Do you have any advice for me?  I see my primary Dr. in a week, and the dermatologist who prescribed this in two weeks.  I'm so sorry that I ever used this ---I was fine before...thanks for your help.

Anonymous
g.t.
4/17/09 12:10pm

just to clarify, because I've also started Aldara: are you only putting it on the tiny cancer spot on your chest + 1 cm around and seeing this crazy result, or are you rubbing the stuff into a large area???

Anonymous
jen
9/ 3/09 4:22pm

if your drem. doctor is good i would go with mohs. i have had it 12 times on my nose and the first 5 mohs you couldnt even tell it. but now i'm getting ready to the aldara and efudex.

9/ 6/11 6:01am

Rebecca - I had Moh's surgery on the side of my face three years ago.  What was the "root" of a tumor inside my cheek came out on my nostril.  My derm kept "freezing" it off for YEARS.  On the advice of a friend, I went to another derm, who biopsied, and the next thing I knew, I was under the knife having Moh's.  Thank God for that.  What the first idiot had been freezing off was just a root.  The surgeon told me I may have had to have the flare of my nostril removed and replaced with the tip of my ear.  Long story short, they did not have to do that; but the tumor under my cheek was quite large (totally unnoticeable) and 35 stitches later...I was closed by a wonderful plastic surgeon, and the scar is barely noticeable.  All's well that end's well.  But, I am now on Week 3 of Aldara (sp?) for yet another lesion - this one is pre-squamous - between my eyes.  (The first with Moh's was basal cell.)  Even though it's topical chemo, I am definitely having side effects and feel achy all over plus a wicked headache all the time.  Three more weeks of treatment, wait 4 more weeks, and re-check.  Don't be afraid of the Moh's.  They do a great job.  Just take a tiny margin until all is clear.  Those roots going to my nostril could have gone to my eye.  Couldn't tell I had a tumor the size of a nickel under my cheek at all.  Moh's surgeons do a wonderful job.  Better to get rid of it completely!!!  No worries.  And they say "blondes have more fun".  We all should have stayed out of the sun when we were kids!!! (I'm 57 now, still blonde, but never go in the sun any more.)  LFZ in New Hampshire

3/19/12 4:57pm

Hi ~  I had horrible side effects within ONE day of using Aldara by my lip.  It scared the heck out of me, so I stopped using it immediately.  (I was also Very careful not to get any in my mouth, which could have been practically fatal.)  I had no idea it was actually a topical chemotherapy.  I was then told I needed surgery for the area which was at the Cupid's bow of my upper lip that had been punch biopsied as basal cell carcinoma.  I thought, "NO WAY am I sacrificing any of my little, tiny lips!"  The older I get, the more my body reacts violently to any type of pharmaceutical.  So, online, I researched natural products for BCC and/or squamous cell carcinoma.  Well, I found it:  -CURADERM-  It took away the basal cell carcinoma on my lip leaving no trace, and I didn't even have to worry about it going down my throat.  It is completely natural!  ...Still, the dermatologists scared me to death telling me I must have "masked it, and now it is spreading under the skin." They scared me into MOHS surgery, and, as it turned out, it was for nothing.  There were ZERO cancer cells in the very first biopsy.  YIKES!  I was SO mad.  MOHS is great, I guess, IF you need it, and I did NOT!!  Now, I have a little scar and am missing a tiny bit of my tiny upper lip.  I've used Curaderm now on many different areas on my face; some BCCs take longer than others to go away, but the average is around six weeks.  My doctor NEVER asked again me what it was I used, in fact, he never even came in to tell me there was no cancer in the first (and only) biopsy.  He never uttered a word when he sewed me up.  Yup, if it gets out that Curaderm can cure BCC and squamous cell carcinoma, American dermatologists would be out of a job.  The doctors are, apparently, much more patient-friendly in England, where Curaderm was developed.

Anonymous
Pamela Hook
2/23/08 1:28pm
I decided to use Aldera on my lip line which constantly was lined w/ dry, flakey skin.  No matter what I did it wouldn't go away.  My son was using Aldera for warts on is foot.  I figured since warts are started by a virus like cancer it might work.  The medicine is very expensive so I thought it was worth a try. When I first started putting it on at night an ugly spot popped out.  This was my clue to ease off on the medicine because I felt this spot meant the medicine must be eating away at the cancer or pre-cancer.  Then I determined I should Keep it clean w/either alcohol or proxide so as not to get the wound infected.  After dry, I followed up w/ Neosporin Antiobiotic w/ pain relief ing. Let it rest a few days before putting on more Aldera.  Kept repeating the process & before you know it all dryness is gone.  Before this treatment all I could think about was how I would be disfigured for life w/ surgeries on my lips.  The spot also cleared up perfectly.  When applying Aldera you must be careful to only apply to the affected area.  If not careful it can leave a little white spot.
So don't use more than you need to and wash your hand after applying.  Sometimes I dot it on w/ a Q-tip.  I also used it on a spot which had been surgically removed by a plastics doc.  He was careful not go too deep but it didn't get it all.  I followed up and its all gone.  Please don't do this stuff without checking w/your doc.  You have to make sure that its not melonoma.  It' is a deadly cancer which requires more rigorous treatment and you need to be under a doctors care.  One more note of caution.  If you use Aldera, cover up the wound if its going to be exposed to the sun.  This is why I apply at night.  Good luck.
Anonymous
quijibored
9/10/08 11:56pm

You are correct. Most people who have problems with Aldara either do not receive proper instruction beforehand or are not told that the skin lesion to be treated can get real ugly before it heals. I have treated numerous squamous cell skin cancers on my forearms that were about the size of an eraser tip before starting Aldara treatment but they reacted so strongly to the Aldara that within a couple weeks it made a big crusty scabby sore about an inch in size. The good news is that when you have a big reaction like this it means your immune system is reacting strongly to destroy the cancer and once you have a significant reaction going on for about a month you can just quit treating with the Aldara and let the lesion heal up. It may take a month or longer for the scabby crust to heal and the scab to fall off but then the skin heals properly and without scarring.

 

It does take some getting used to seeing this big scabby sore on yourself but you have to trust that the medicine will work and for me it almost always does and always heals up if given enough time. There are a few basal cells or squamous cells that for whatever reason will not respond completely or quickly enough - within 2 - three month courses of Aldara and then I go ahead and have the remaining lesions surgically excised but most of the time the Aldara works just fine, often in a month or less rather than the predicted 2-3 months of therapy.

Anonymous
Stephen
9/24/09 10:44pm

Your response was perfect.  I have used Aldara and I wish I read this web sit before doing anything.  The scab that occurs means the Aldara is working for you.  Research and using any product the correct way is the key.

Anonymous
Chan
3/10/08 1:18am

 

I find the website that sell the aldara online which i buy it alrady. It very cheap Aldara 5% cream (imiquimod) 12 sachets by 3M Pharma only 140US$ at http://www.edrughouse.com/catalog/main_product.php?cPath=30

 

I attempt to find the cheper, if some one in site can find, please told me too.

Anonymous
Anonymous
10/28/08 9:18am

Thank you for this information. I have a history of basil cell cancer and will start the aldara soon for two new places on my face. I was wondering about studies done for this medicine and if there are any bad side effects?

I just found your site and find it very informative. Thank you again.

Anonymous
William
10/28/08 12:09pm

For information about Aldara please go to http://www.edrughouse.com/Aldara.html

 

you can find aldara online and take it (aldara) which cheaper than the other website too.

 

 

Anonymous
Sue
12/28/08 9:46am

For a small BCC there are also other options, even for the face.  Radiation, and burning it off.  Burning leaves a white patch where the BCC was, so it may not be for everyone.  But, Mohs also changes the original appearance and leaves a scar. I would have chosen to burn mine off my nose had I known that Mohs would cut my nose the entire length from eyebrows to between the nostrils, and leave me with a different shaped nose. The BCC was shallow (one Mohs slice removed it) and small.  Mohs was overkill.  People worry too much that BCC is 'cancer'.  It is slow growing and non-malignant.  Stay calm and definitely try Aldara first.  Once the course if done, there is no scars or aftermath.

Sue

Anonymous
dianacuttrell
4/16/09 1:21pm

I am a 52 year old woman who has been active all my life, surfing and horse back riding with lots of sun exposure.

 

I had a BCC on my lip for years and treated it with Aldara and Efudex, I don't think I did the treatment correctly and the BCC never went away only got larger.  I had Mohs surgery done in late November '08 and am still recovering from it.  It was very traumatic and I was unaware that I would have stitches starting from the side of my nose to the corner of my mouth.  My surgeon did a fantastic job, but I still have swelling and some discoloration.  I am currently being treated with a Vbeam to remove the redness.  The good news is that BCC is gone, the bad news is I am not completely back to normal still having numbness and swelling along with the discoloration.

 

Since the surgery, two smaller BCC's have surfaced, my surgeon, wants to remove them with Mohs surgery (again), my dermatologist wants to treat less aggressivily.  From reading the comments on this site, I want to try the creams instead of surgery,  With Mohs there would definitely be huge scars, one is under my eye and the other on the right side of my nose.  I can't bear to go through the surgery again and I am very scared. 

 

From reading other's results using the cream, I will give it a try and be extremely diligent with the directions on how to use it correctly.  Any comments would be appreciated.

Anonymous
DH
5/ 1/09 6:18pm

I'm also 52 and was diagnosed with BCC on my nose (top and towards tip) almost 8 weeks ago now. Have been using Aldara 3X week as prescribed by my dermatologist (He said to use a very small amount...that more is NOT better. He also warned me that it would eventually look 'hideous' for a while, but that that was better than the alternative.) Well, I've had no side effects at all other than itchiness (tolerable) and a slight burning nights I use it. My doctor was right- it looks absolutely hideous and for the past 2 weeks I try to just go to work and not run too many errands as I'm very self-conscious about it. My 8 weeks is up this Sunday and I go back to the dermatologist this coming Tuesday. If the Aldara has worked, it will have been worth it...much better than a scar (and I'm hoping this big ol' scabby thing doesn't leave a scar...)! Good luck and remember to use a SMALL amount-

Anonymous
Giacomo
9/20/09 1:14am

I've used Aldara and Efudex for 'Years' due to having Gorlin-Goltz Syndrome = Hundreds of Basal Cell Carcinoma's all over my body. If you 'Use as DIRECTED' you will not have problems UNLESS you're 'Allergic to the product' like any other product or food, etc. It's life folks! I know of people who 'Used TOO MUCH Aldara, when they were told to use A VERY SMALL AMOUNT, like the end of a Ball Point Pen! People do not listen and do it there own way, think using MORE is better (it is not - ever) and suffer the consequences. Creams are better than surgery! Duh! UndecidedYou will have 'some minor redness for months. Maybe even years. Slight. Unless you're a Narcissist don't worry the redness is very minor. I use to have perfect skin, but played tennis 8 hours a day for 30 years and surfed and ran on the beach daily, where I grew up. I am loaded with SKIN CANCER NOW! Plus, I had no idea this rare skin cancer 'Genetic Problem' runs in my family. My God. Use the Cream when you can. Far better than surgery or freezing. Cryosurgery leaves permanent 'scarring too' The pigment of skin is forever damaged. USE THE DAMN CREAMS AS DIRECTED AND ALMOST ALL PATIENTS WILL BE FINE. 24 years of experience telling you this! Former Semi-Pro tennis Player - Malibu, Calif.

Anonymous
slw
6/18/10 4:34pm

I had an area on the side of my nose frozen 5yrs. ago.  Last year  it started to reappear so I went to the doctor who decided to freeze again- it did nothing! Then I had to try effudix, this made the area a lot worse and larger, it kept bleeding. She advised me not to use it any more and suggested I could see a dermatologist.  I am now due for a biopsy and possible mohs surgery(this scares me).  I am using Aldara on a small place she noticed on my chest. It has brought up 3 sore patches around the place but nothing in the middle, I am wondering has it worked...its week 5.  I am using it 5 on an 2 nights off

Anonymous
Anonymous
1/22/09 1:08pm

I was diagnosed with chelitis glandularis. I tried carac for a month with few results. Doctor now suggests Aldara. What will the difference be?

Anonymous
Jellybean
7/13/09 2:19pm

I am using Cara for warts on my hands and after 1.5 weeks, I see noticable areas where the wart disappeared. Carac is great for these. I use quite a generous amount and put gloves on, then go to sleep. I tried Aldara on one hand and it is vicious. It eats away at the wart leaving an ugly sore. Must not use too much at a time, and stop if the sore is getting bad.

Anonymous
AJ
2/23/09 4:03pm

I used Aldara cream successfully for a small AK spot on my face.  I also green tea and believe that helps also.  Highly recommend.

Anonymous
Jennifer
3/28/09 1:50pm

Hi, I was just prescribed Aldara to treat 27 BCC lesions in various areas on my upper body. This is my 3rd round with it - the first two times it was prescribed (years ago, for just one lesion) completely failed; the cancer returned within months. My doctor prescribed it this time due to the number of lesions I have, which requires a LOT of Aldara each evening. Don't believe that there aren't systemic side effects - by day four I had completely lost my appetite, had become listless and tired, and can hardly lift my arms due to swollen lymph nodes. All of that in addition to the painful sores at the site of application. It's a SERIOUS drug! Expect side effects and be careful using it.

Anonymous
Giacomo
9/20/09 1:23am

If your doctor is prescribing this for use on 27 BCC or ANY skin cancer 'You should consider changing dermatologists'. My God, this is insane! It is NOT for use on 'More than 'One REGION at a time'. You are putting so much TOXIN in you it is funny. 'Of course, it'll take longer to get them ALL but, using this on so many (27) at one time is 'Not the right treatment Regiment/Protocol'. Call 3M and ask them. NOW! and then get a 'Second Opinion' ASAP. ALDARA ON 27 BCC ALL AT ONCE??? I cannot believe I just read this! I am sick over it.....CALL ANOTHER DERM ASAP.

 

PLUS, WITH SO MANY BCC (YES, I HAVE HAD HUNDREDS AND HAVE BEEN FIGHTING BCC'S FOR 24 YEARS, SO YES, I DO KNOW. I'VE HAD 34 DERMS AND MD'S) YOU SHOULD TRY 'A COMBINATION OF THERAPIES' AS I AM....PHOTO-DYNAMIC THERAPY, ALDARA, EFUDEX, MOHS (WHEN NECESSARY), CRYOSURGERY, AND MORE....YOU NEED TO READ AL YOU CAN AND TAKE CARE OF YOURSELF. IT IS YOUR BODY! 'KNOWLEDGE IS POWER' AND IT MIGHT JUST SAVE YOUR LIFE.....27? I cannot believe you're applying aldara to ALL of them!

4/11/09 6:52pm

Has anyone on this forum ever used CYMILIUM or CURADERM for treatment of skin cancer?

 

Do you think these products would work?

 

http://www.cymilium.com/SkinCancer.html

 

http://www.curaderm.net/technology/diseasestreatablenmc.aspx

 

Anonymous
Anonymous
5/13/09 8:54pm

I've used cymillium, but not with much success. I have now undergone one Moh's on my face and am using Aldara on my chest. Check out topicalinfo.org for lots of great info on these and many other alternative skin cancer treatments. Especially check the forums for many personal experiences. Good luck and God bless.

Anonymous
anonymous
11/15/10 11:59am

When I posted the above in May 2009 I had just started the Aldara. The side effects were horrible for me and I believe it caused me to have a miscarriage in Aug'09. I was sick, sick, sick from it. My friends had to help me take care of my kids. I felt like I had the flu constantly. It effects your immune system which is why I think it effected my pregnancy, but maybe it was a coincidence; I'll never know for sure.

 

Proceed with extreme caution if you decide to use it. On the other hand my 2 lesions on my chest are GONE. They were the size of a dime and a pencil eraser. By the time I finished the Aldara, the scabs had grown to the size of almost a dollar bill and a quarter respectively. They then healed over a few weeks and they are now light pink smooth skin.

 

I hope this info helps someone to make an informed decision.

Anonymous
Bryon
11/16/09 12:59pm

Aldara should be called "Bloody Murder" so that patients will know what to expect from it. I used it exactly as directed, only a tiny bit on a q-tip rubbed on the spot of basal cell carcinoma. Next day the spot was red and my body ached all over. The second day the sore was worse and oozing. After four days I couldn't stand the pain and discontinued. The spot on my face now looks like I was blasted by a 12 guage shot gun with blood and puss coming out. Since I stopped using Aldara most the body aches have stopped, but I feel pressure in my head and an ache in my neck.

Anonymous
S Long
11/24/09 2:22pm

I am just finishing a 4 week treatment of twice a day applied to my upper chest and collar area. My skin is fried and itching. Today is my last day applying the cream. What can I use to help the burn and itch while I heal? It is painful.

Anonymous
Anonymous
12/15/09 7:59pm

please advise what help can be given for bur 7 itch after 4 weeks of Aldara & scab partly fell off

Anonymous
Anonymous
1/ 3/10 6:03pm

i have put a miniscule amount of aldera on left corner of lip for ak for 9 days, and my upper and lower lips  on left now have open sores and blisters...very painful. don't know if it is from cream or it has caused fever blisters-  is this a usual reaction- what can i do for pain and do i keep doing this for 5 weeks?  i was told 5xweek, and 2 days off. seems like more times a week than some i have read about- what do u suggest?

Anonymous
aj
1/ 4/10 5:56pm

I have been using efudex for over 30 years and aldara for10 or so for skin pre cancers. I have been told that once the lesion gets red and raised that the job is done, and you need to stop using it. I kept on using aldara thinking that the more red it got, the more it was working. I was informed to stop when the reaction became definite. My experience is that aldara works very quickly on me - twice a day for 4 or 5 days and then I quit. And I almost have an ugly red reaction, but  places that were rough scab up and  go away after my skin stops reacting. I always use silver sulfadiazine cream on my affected areas afterwards. This is a cream used on burn patients and is also great for diaper rash. Also over the counter. I seriously think the majority of problems from aldara is from extended overuse. Efudex has never been as effective  for me but I use it sometimes because it's effects never seems to be so severe.

Anonymous
Anonymous
1/ 5/10 11:04pm

It is interesting that I am in the 15th week of using Aldara on both my face and chest.  I have done Efudex 20 years ago and have had numerous pre cancerous spots taken off over the years.  When Aldara was recommended by my dermatologist, I was not particularly excited about a 16 week period.  The application to my hairline on my face has actually almost cleared up,  and I am in the 15th week.  However, on my upper chest and this is a period of october through January, thank goodness, I look like raw hamburger.  I don't know if this is the fact that because of the temperature,  the chest area does not have the normal fresh air exposure, but it will be interesting to see how long it actually takes to return to normal.  However, after watching the procedure for my husbands MOHr surgery on his ear, and the pain he went through, I think that I am very lucky that the Aldara is available.

Anonymous
slilly
8/26/10 7:09pm

I just started on the efudex cream two weeks ago ... face, neck, chest, arms ... and my skin has reacted quickly. Just saw my derm. today and she recommends using efudex until skin is clear. Says research shows that this is the most effective way to make sure the cancers have been killed. However, she also recommends diluting it to a 1 part efudex-4 parts 1% hydrocortizone lotion once the spots have become prominent and have just started to break open. This eases the redness/pain of full strength and she finds it is just as effective at this point. I really hope so, because the irritation is tremendous and I just can't imagine 3-4 months of this!

1/22/11 12:30am

My eye surgeon (also a plastic) wants to start Aldara on tip of my eyelid. Have had two SCC & many ak already removed. Says he has had success with over 50 patients. I'm slightly apprehensive. (Have also done the full face Effudex thing 10 years ago.)

5/ 1/11 9:16am

This is the most ludicrous discussions on the use of Aldara I have seen in over 11 years of research concerning this drug.  Doctors are using this drug in all the wrong places and the patients are "assuming" Aldara is like all other creams.  More especially Efudex, Carac, and others.  This is simply not the case!  It is very dangerous and has thousands of injured victims on file some of which are permanently destroyed, both health and livelihoods and family units.  PUT IT ON OR NEAR THE EYES?  For God's sake, in my opinion, the doctor that prescribed Aldara in this fashion should be brought up on criminal charges, not hailed as some type of high ranking licensed physician.  No one, I mean no one anywhere, FDA, 3M, Graceway, no one, ever stated anything but warnings "AGAINST" applying Aldara near the eyes, nose, mouth, and lips.  Do you want to know the reason?  Your doctor will obviously not know nor care.  Aldara attacks mucous membrane tissue and destroys it in the most agressive immune response you will ever witness.  Place near the eye: expect permanent tear duct destruction.  Placed on the lips:  risks plastic resconstructive surgery that is usually unsuccessful.  This my friends is not idle reports from someone disgruntled with Aldara or 3M or anyone else.  These are facts about this drug and there are thousands of real victims behind every word I typed here to back it all up.  Scare tactics?  No.  Just the truth that you obviously are not getting from your doctors or the literature.  Read the insert document in Aldara. Read...........

4/23/11 10:13am

When I started using this cream on my scalp I was told that some of my hair might fall out.  That never happened.  The hair around this spot is thicker.  I'm wondering if the hair can slow up the healing process because the scab won't fall off.  Not sure when to stop using the cream.

6/ 1/11 5:45am

I was given Aldara to treat what was diagnosed as BCC.  I applied the cream 6x/week. By the 3rd week, the 'tumors' on my arm were badly burned and sported very large scabs, each surrounded by fiery red skin.

 

Worse, new little growths began to emerge and spread.  Within days they too grew into large, bubbly masses.  As I began to treat each new one, more appeared, sprouting up like mushrooms until my entire lower forearm was dotted with crusty sores and the skin was bright red.

 

After the original diagnosis, I traveled to a small village in southern Turkey -- no dermatologist here to see, treat or biopsy the remains of this mess. I suspended the treatment and decided to let it all heal, then I will drive 3 hours to a large hospital.  Now, 2 months after beginning this treatment, the original 'tumor/wart ?' now shows up as a series of tiny, hard cysts -- lumps on the original site.  Many of the other growths have receded and flattened, some others remain as raised crusty bumps.  The skin redness is now pink, no idea if it will go away or remain permanently discolored.  I am now wondering if there was a wrong diagnosis in the beginning? Perhaps these spreading bumps are/were warts or herpes rather than BCC? 

Anonymous
Teresa
8/19/11 2:10am

I am currently applying efudex on my arms and neck and for the past 3 days have been experiencing headaches and/or a throbbing and annoying pain behind the rt. eye.

 

Can chemortherapy drugs do that?  Thanks so much!

3/21/12 8:54am

You can use a 100% natural cream to treat skin cancer. You do not need to use chemicals ,instead you can use herbs. http://johnnys.biz

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By Kevin Berman, MD, PhD, Health Guide— Last Modified: 05/25/12, First Published: 03/19/07