Sign in

or Register now

SkinCancerConnection.com

See all of our health sites at www.HealthCentral.com
Saturday, July, 26, 2008

Efudex, Aldara and Other Skin Cancer Topical Chemo Creams

by  Kevin Berman, MD, PhD
Monday, March 19, 2007
Kevin Berman, MD, PhD
Kevin Berman, MD, PhD
Close
Dermatologist

Kevin Berman, M.D., Ph.D., is a practicing dermatologist in Atlanta...

Kevin Berman, MD, PhD

Recent Posts:
View All

Hi everyone.  Today I want to talk about the two topical therapies used to treat certain

  1. aldera
    Anonymous
    Wednesday, March 21, 2007 at 01:44 AM
    Had a slow growing stickey skin cancer for 10+years on chest.  Half-dollar sized.  Freeze, Efudex, surgery=no cure and no change.  Finally an Aldera course.  Now, 4 years later, still no spot.
    reply
  2. aldara
    MM
    Sunday, April 01, 2007 at 12:51 PM
    Does someone have an answer?   Is it OK to use makeup and sunscreen lotion when you go out while you are using aldara 2 nights a week for 4 months?
    I'd appreciate any info you might have.

    reply
  3. Carcinoma in situ VIN III, Severe squamous dysplasia
    Esra
    Friday, May 25, 2007 at 09:15 PM

    Dr Berman,


    I have just been diagnosed with above in the vulva. I have been given Aldara to use for the next 2 months. Have done some research and found some terrifying information as well as good. There is a website Aldara1.com which 3M tried to take down but lost. Also 3M Pharmaceuticals settle a lawsuit outside of courts for a man who got extremely sick. Please advise how come Aldara is being prescribed? If this is true how can doctors play russian rullet with the public? Please help


    reply
    re: Carcinoma in situ VIN III, Severe squamous dysplasia
    glad to serve
    Thursday, July 24, 2008 at 01:27 PM
    I was talking to the various pharmaceutical companies and I learned that once a drug is FDA approved a doctor can use it for anything he/she chooses to prescribe it for. I too am suffering greatly from misapplication of a drug. Efudex is labled specifically not for intravaginal use. My doctor said "trust me, I know what I am doing". Six months later, suffering from chemical vaginitis and chemically induced cystitis as confirmed by cystoscope I asked my gynocologist if they still stood by "trust me". I was told that the urologist has a right to his opinion but the gynocologist still feels it is perfectly safe. I wish I could trade bodies with that doctor for one day, so they could experience what they are so coldly dismissing. This is extremely painful, unnecessary and has put the breaks on all of my personal plans since February.
    reply
  4. Aldara
    Anonymous
    Tuesday, June 26, 2007 at 06:11 PM
    Have been treating my face and chest for3+ weeks 2x's week with Aldara. Have large open oozing sores, diahreah for 3 weeks and horrific flu like symptoms for 2 days after each treatment..pins and needle feeling throughout my body, joint and muscle aches with slight fever. I have been megadosing vitamin c thinking I was getting a flu. Curios about these symptoms I researched Aldara on line and was horrified to read how dangerous it can be. Many people including physicians are trying to get this off the market.
    reply
  5. Efudex as Vaginal Cancer treatment
    LMA
    Thursday, August 23, 2007 at 01:31 AM
    I am starting this treatment soon for vaginal pre-cancer.  Any tips.  I am scared of the pain i have been warned about.
    reply
    re: Efudex as Vaginal Cancer treatment
    Robyn N.
    Thursday, September 20, 2007 at 09:52 PM
    It is a horrendous treatment. I went hrough six treatments before having to stop, pain, nausea, burning. First get a second opinion from a gyno-oncologist. My second opinion oncologist said he has not used this drug for 15 years, that the treatment was way worse than any cancer. Stop, run and seek a second opinion.
    reply
    re: re: Efudex as Vaginal Cancer treatment
    Linda
    Saturday, December 08, 2007 at 09:59 PM
    Just the opposite for me.  Absolutely no problems.  I read on another website to use petroleum jelly on the outside skin area in case of any burning.  Very very rarely did I feel burning, and when I did, I used the jelly and had absolutely NO problems.  I was scared to death to use it after reading all the "stories" on the Internet, only to find out I had absolutely nothing to fear
    reply
    Efudex as Vaginal Cancer treatment
    Marlena
    Saturday, December 29, 2007 at 03:06 PM

    I just began it last night and am very glad to see your note here.  Thanks and it gives me hope that I won't come out of this horrified.

     


    reply
    re: Efudex as Vaginal Cancer treatment
    Marlena
    Sunday, January 06, 2008 at 10:08 AM
    Update: I completed my 7 days of therapy.  Used Zinc Oxide on outside and no burning but the damage on the inside is horrendous.  Since stopping, my vaginal opening is sealing up. Nothing is stopping it.  It is painful to reopen.  Bath after bath to give myself relief from dryness and pain.  I don't want to do the next treatment.  I am scared to death.  I don't know what the final healing from this course of treatment will be.  Any pointers from anyone on relief or how to stop this closure from happening?
    reply
    re: re: Efudex as Vaginal Cancer treatment
    Janice
    Friday, January 18, 2008 at 07:33 PM

    I went through this nine years ago. The pain is no fun. I used the petroleum jelly even around the opening.  The best way I found to insert the applicator with all the raw flesh is that I put just a little bit of lubricant on the tip  of the applicator, put one foot up on the toilet seat and inserted it as fast as I could. 

     

    After all is said and done, it wasn't fun but I have not had one irregular pap since, and I battled cancer for years, had a hysterectomy, went through interferon injections, laser and I finally got relief after this treatment.


    reply
    re: re: Efudex as Vaginal Cancer treatment
    glad to serve
    Thursday, July 24, 2008 at 01:16 PM

    Efudex is a dangerous product with serious complications.  http://www.getoomph.com/pdfs/EfudexPatientBrochure.pdf Read page three of this link and you will see that the company warns against intravaginal use due to vaginal necrosis, ulcerarations, and other local reactions.  I can personally tell you that it does not target bad cells.  It affects and kills every cell that it comes in contact with.  I can see where it is entirely capable of sealing off a vaginal opening.  The best thing you can do is keep vaseline or neosporin on the affected area.  Once all the tissue is killed off, the body's natural healing process will seal together raw tissue.  I personally underwent this treatment without a full understanding of how much damage it would do.  It caused me to suffer from intense pain and swelling due chemical vaginitis.  I also have suffered from chemically induced cystitis according to the cystoscope performed by my Urologist.  EVERYONE should know that this drug is so dangerous that the FDA gave it their Box Warning:High Alert Medication: "The Institute for Safe Medication Practices includes this medication among its list of drugs which have a heightened risk of causing significant patient harm when used in error."  This is copied from the Merck Manual website. This drug is supposed to administered as a last option and only by a physician trained in the safe use of this drug. I began treatment intravaginally in February and I am still suffering greatly.  Never trust a doctor who tells ou that even though the box says specifically NOT FOR INTRAVAGINAL USE, that they know what they are doing and it is perfectly safe.  It is not safe!  That is why all these warnings are posted on the internet.  Click on this link to find out about studies on the success rate of this treatment.  The study shows that folks on placebo had a higher recovery rate than those on Efudex intravaginally.  Why?  Most likely the weakened tissue was more susceptble to dysplasia/virus cells.   http://www.hindawi.com/getarticle.aspx?doi=10.1155/s1064744999000319     


    reply
  6. Carac Cream
    jimbo61
    Sunday, September 09, 2007 at 08:39 PM
    I am on day 10 of 2X day Carac Cream for AK's on my face.  Not a terrible reaction yet.  I hear that the third week is the worse.  What is the difference between Effudex and Carac??
    reply
    re: Carac Cream
    RHONDA44
    Friday, March 21, 2008 at 09:02 PM

    Jimbo61,

     

    Im on 9th day of Carac tonight.  I wanted to get on your site of talk to you here because I tried to get on you skin journey site and it would not let me.  I hope you reply.. I have questions.


    reply
    re: re: Carac Cream
    jimbo61
    Friday, March 21, 2008 at 09:22 PM

    Hi Rhonda,

    Sorry I took my site down to work on other issues.  I would be more than happy to answer any questions you may have.  My email is Jfoster1961@msn.com

    My best,

    Jim 


    reply
  7. painful!
    Amanda
    Friday, January 18, 2008 at 10:20 AM
    I've been on the treatment for about two weeks now, taking it 3 times a week. For the past week, I've woken up with insane itching around three or four in the morning every morning. It's getting to the point where I'm having trouble going to the bathroom and for the life of me can't ignore the problems this is causing me. I can deal with a lot, but it's beginning to be very bothersome. Anything I can use to help the pain/itching? I tried to call my doctor this morning, but after three failed attempts and the fact that I can't afford a doctor's visit [thanks to having no insurance!] I'm not sure what else to do.
    reply
    re: painful!
    Amanda
    Friday, January 18, 2008 at 10:21 AM
    Sorry, I didn't make it clear that I was using the Aldara cream.
    reply
    re: painful!
    ted
    Monday, January 21, 2008 at 04:47 PM
    hang in there, Ive just been through the same symptoms, I found that dehydration is a problem, causing the itching, take plenty of fluids and 2 neurofen before bed, also heaps and heaps of moisturiser after you finish the efudex treatment
    reply
  8. Untitled Comment
    laura holt
    Thursday, February 07, 2008 at 09:35 PM
    I am currently using aldara and it is not easy. It is painful after 3 weeks of using it 5 days a week. the areas on my face where I am applying it look horrible, and I have to work everyday,it is difficult, really hard. I have had skin cancer for over 20 years and I am 47. I have used effudex, have had mohs surgery. It is really difficult, but I keep thinking I will be done with this soon and then I will look normal for a while. I realize many people have many serious health issues, but sometimes this really gets me down. Please everyone, just try to get through every day.
    reply
    re: Untitled Comment
    Rebecca
    Sunday, February 10, 2008 at 11:42 AM
    Laura -  I hope your weeks of treatment go fast for you.  I am facing the decision of either doing Mohs or Aldara for a bcc on the side of my nose.  If it weren't in the middle of my face it would be easy to pick surgery and just have a scar somewhere.  But because it would be in such an obvious place, I am thinking that maybe I should try to live though the Aldara for 8 weeks and not have to live with a scar for the rest of my life.  Why if you have done surgery in the past did you pick Aldara this time?  Do you regret it?  Am I going to better off with just doing the surgery?  Any advise would be appreciated!    Reb
    reply
    re: Untitled Comment
    upc
    Saturday, June 14, 2008 at 12:28 AM

    I began aldara three weeks ago, I have taken breaks during that time when I did not use it, and now I have stopped forever.  I had a tiny cancer on my  chest so small that even the dermatologists really didn't know where it was.  But I really didn't want the surgery, so thought that using aldara was the perfect answer.  Now I am so sorry that I let anyone do anything, my whole upper chest is a mass of open sores, I'm putting neoporesporin on it, I have to cover it during the day, it bleeds and sticks to my shirt, I leave it exposed at night, but it doesn't seem to be healing.  I'm 76 years old, have arthritis, but am otherwise healthy.  Do you have any advice for me?  I see my primary Dr. in a week, and the dermatologist who prescribed this in two weeks.  I'm so sorry that I ever used this ---I was fine before...thanks for your help.


    reply
  9. How u use Aldera is the Key
    Pamela Hook
    Saturday, February 23, 2008 at 01:28 PM
    I decided to use Aldera on my lip line which constantly was lined w/ dry, flakey skin.  No matter what I did it wouldn't go away.  My son was using Aldera for warts on is foot.  I figured since warts are started by a virus like cancer it might work.  The medicine is very expensive so I thought it was worth a try. When I first started putting it on at night an ugly spot popped out.  This was my clue to ease off on the medicine because I felt this spot meant the medicine must be eating away at the cancer or pre-cancer.  Then I determined I should Keep it clean w/either alcohol or proxide so as not to get the wound infected.  After dry, I followed up w/ Neosporin Antiobiotic w/ pain relief ing. Let it rest a few days before putting on more Aldera.  Kept repeating the process & before you know it all dryness is gone.  Before this treatment all I could think about was how I would be disfigured for life w/ surgeries on my lips.  The spot also cleared up perfectly.  When applying Aldera you must be careful to only apply to the affected area.  If not careful it can leave a little white spot.
    So don't use more than you need to and wash your hand after applying.  Sometimes I dot it on w/ a Q-tip.  I also used it on a spot which had been surgically removed by a plastics doc.  He was careful not go too deep but it didn't get it all.  I followed up and its all gone.  Please don't do this stuff without checking w/your doc.  You have to make sure that its not melonoma.  It' is a deadly cancer which requires more rigorous treatment and you need to be under a doctors care.  One more note of caution.  If you use Aldera, cover up the wound if its going to be exposed to the sun.  This is why I apply at night.  Good luck.

    reply
  10. This is the cheapest aldara?
    Chan
    Monday, March 10, 2008 at 01:18 AM

     

    I find the website that sell the aldara online which i buy it alrady. It very cheap Aldara 5% cream (imiquimod) 12 sachets by 3M Pharma only 140US$ at http://www.edrughouse.com/catalog/main_product.php?cPath=30

     

    I attempt to find the cheper, if some one in site can find, please told me too.


    reply

Ask a Question

Get answers from our experts and community members.

Answer a Question

skin wrap

Answer This View all questions >
Healthcare 08