In the early 20th century, Swedish physician Henrik Sjögren (SHOW-gren) first described a group of women whose chronic arthritis was accompanied by dry eyes and dry mouth. Sjögren's syndrome (SS) can develop on its own (called “primary SS”) or as a complication of another autoimmune disorder (called “secondary SS”), most often lupus or rheumatoid arthritis. Symptoms vary in type and intensity, and serious complications are rare.
Sjögren's syndrome is an inflammatory disease with unknown cause that can affect many different parts of the body, but most often affects the tear and saliva glands. Patients with this condition may notice irritation, a gritty feeling, or painful burning in the eyes. Dry mouth or difficulty eating dry foods, and swelling of the glands around the face and neck. Some patients experience dryness of other mucous membranes (such as the nasal passages, throat, and vagina) and skin.
Most of the complica...
It’s flu season. You probably know someone who is down and out, with a fever, body aches, a sore throat and cough. But what if they also have a rash? Is this a symptom of the flu? Or does it mean something else is going on?
While a rash is not typically a symptom of the flu, that doesn’t mean it isn’t. Influenza affects many parts of your body and not everyone reacts the same way. If you are susceptible to allergic skin reactions, it is possible that your rash is a symptom of the flu. However, if you develop a rash with flu-like symptoms, you should talk to your doctor. Some of the more common medical conditions that include aches, fever and rashes include:
Shingles - Shingles is caused by the chicken-pox virus and can be dormant in the body for many years before it appears. It usually starts with a painful rash on the face or body, however, early symptoms can include flu-like symptoms, headaches and sensitivity to light.
Rocky Mountain Spotted Fever - Although ...
The medication sunitinib, which is approved for the treatment of kidney cancer and gastrointestinal stromal cancer, may also help patients with metastatic melanoma according to an article in the March, 2012 issue of Clinical Cancer Research. This new medication uses a patient's own tumor cells to create a customized treatment plan.
The drug recently completed Phase II clinical trials. During the testing is was shown to be effective in treating skin cancer which occurs on parts of the body not normally exposed to the sun, such as in the mouth, on the soles of the feet and the palms of the hand. This type of cancer has previously been difficult to treat because it is resistant to chemotherapy, with only 5 to 20 percent of patients responding well to it. The new drug, however, had a positive response in over one half of patients in the trial.
Sunitinib works by turning off a protein within the tumor. This protein is created by mutations within the genes and when "turned off...
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