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In the early 20th century, Swedish physician Henrik Sjögren (SHOW-gren) first described a group of women whose chronic arthritis was accompanied by dry eyes and dry mouth. Sjögren's syndrome (SS) can develop on its own (called “primary SS”) or as a complication of another autoimmune disorder (called “secondary SS”), most often lupus or rheumatoid arthritis. Symptoms vary in type and intensity, and serious complications are rare.
Sjögren's syndrome is an inflammatory disease with unknown cause that can affect many different parts of the body, but most often affects the tear and saliva glands. Patients with this condition may notice irritation, a gritty feeling, or painful burning in the eyes. Dry mouth or difficulty eating dry foods, and swelling of the glands around the face and neck. Some patients experience dryness of other mucous membranes (such as the nasal passages, throat, and vagina) and skin.
Most of the complica...
Generic Name: EMOLLIENTS - TOPICAL Diaper Rash Relief Top Uses
This medication has 2 types of ingredients (emollient,
keratolytic) that work together to treat or prevent dry, rough, scaly, itchy
skin (e.g., eczema, keratosis, xerosis). Dry skin is caused by a loss of water
in the upper layer of the skin. Emollients are substances that soften and
moisturize the skin and decrease itching and flaking. Emollients/moisturizers
work by forming an oily layer on the top of the skin that traps water in the
skin. Petrolatum, lanolin, mineral oil, and dimethicone are common
Lactic acid, salicylic acid, and urea are keratolytics.
They increase moisture in the skin by softening/dissolving the horny substance
(keratin) holding the top layer of skin cells together. This helps the dead
skin cells fall off and helps the skin keep more water in. Higher strengths of
urea are used to treat corns, callous, and some nail problems (e.g., ingrow...
The medication sunitinib, which is approved for the treatment of kidney cancer and gastrointestinal stromal cancer, may also help patients with metastatic melanoma according to an article in the March, 2012 issue of Clinical Cancer Research. This new medication uses a patient's own tumor cells to create a customized treatment plan.
The drug recently completed Phase II clinical trials. During the testing is was shown to be effective in treating skin cancer which occurs on parts of the body not normally exposed to the sun, such as in the mouth, on the soles of the feet and the palms of the hand. This type of cancer has previously been difficult to treat because it is resistant to chemotherapy, with only 5 to 20 percent of patients responding well to it. The new drug, however, had a positive response in over one half of patients in the trial.
Sunitinib works by turning off a protein within the tumor. This protein is created by mutations within the genes and when "turned off...
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