Dyshidrosis; Pompholyx
Scratching the hands when they itch only makes the condition worse. Yet scratching can be hard to stop.
Anti-itch medicines taken by mouth, such as diphenhydramine (Benadryl) and loratiadine (such as Claritin), may help you break this cycle. If you scratch while asleep, take an anti-itch medicine before bed.
Ointments or creams should be used on the hands at least two times per day, and after every hand washing.
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Source: ADAM Encyclopedia
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