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Hi Deanna - You really do need to speak with all involved on the dangesr vs the effectiveness of your medications.  I also think you should be able to speak to your pharmacisit and he/she can flag you if there are possible interactions.   I'm not sure of the anti depressant you are taking or the sleep aid.  Try linking on the links to see if we list those you have been prescribed.   As well, Strattera is also used as a medication for ADHD - Attention Deficit Hyperactivity Disorder.  So it is possible that your doctor (if it in fact is only one doctor prescribing all three) does believe these three meds can support your issues effectively.  You can review the Precautions and Side Effects and the Drug Interactions of this drug.   However if you are having any concerns, or physical or emotional side effects, you should talk to your doctor or pharmacist.  Good communication is crucial in maintaining a patient doctor relationship.   Hope this helps and all the best, sue (moderator)