Trazodone and Bupropion. So far I have not had any severe reactions but recently found out that my potassium levels were found to be really high. I also take Detrol LA for a tilted bladder. I am on a few other medications including Theophylline, Levoxyl, Zetia, and Xanax Prn. I was recently taking Seroquel, but was concerned because I was sleeping too hard and unable to be awakened for the first four hours of sleep. My question is how dangerous these combinations could be over a period of time. I did take Tazodone years ago for approx. 3 years and became immune. Approx. 2 years ago it was tried again but with same results 100 mg did not make me sleep. That was when I was taking Seroquel and weened myself off just in last month due to fear of inability to wake up in case of emergency. I have had three different professionals tell me three different things and I am beginning to have to increase my dosage of Trazodone and worry that maybe I need a different medication for sleep.




