Provigil Oral

Provigil Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• medications for high blood pressure (e.g., beta blockers such as atenolol/metoprolol, clonidine, guanabenz, methyldopa, prazosin)
• "blood thinners" (e.g., warfarin)
• street drugs (e.g., methamphetamine, MDMA-"ecstasy")
• drugs that affect liver enzymes that remove modafinil from the body (e.g., azole antifungals such as itraconazole/ketoconazole, rifamycins such as rifabutin/rifampin, anti-seizure medications such as carbamazepine/phenobarbital)

Modafinil can speed up or slow down the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs may include certain antidepressants (e.g. TCAs such as clomipramine/desipramine, SSRIs such as fluoxetine, fluvoxamine), cyclosporine, diazepam, phenytoin, propranolol, theophylline, triazolam.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before, during, and after treatment with modafinil. In some cases a serious (possibly fatal) drug interaction may occur.

This medication may decrease the effectiveness of hormonal birth control (e.g., pills, patch, ring). This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication and for 1 month after stopping this medication. Consult your doctor or pharmacist for details.

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients (e.g., pseudoephedrine, ephedra/ma huang) that could increase your heart rate or blood pressure. Ask your pharmacist about the safe use of those products.

Avoid drinking large amounts of beverages containing caffeine (e.g., coffee, tea, cola). Caffeine can increase the side effects of this medication.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.