Narcolepsy And Diabetes Type 1

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Causes


Recent autopsy studies have shown a reduced amount of hypocretin-positive neurons in patients with narcolepsy with cataplexy. Researchers have postulated that some type of immune response may affect these hypocretin cells.

Hypocretin deficiencies might set off the following chemical responses that may produce sleep attacks:

  • Lower levels of histamine, a chemical that promotes wakefulness
  • Low levels of epinephrine (commonly known as adrenaline), a hormone important in alertness and arousal
  • Incre...
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