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Pathophysiology Of Paroxysmal Nocturnal Dyspnoea
Paroxysmal nocturnal hemoglobinuria is a rare disease in which red blood cells break down earlier than normal.
Alternative Names
PNH
Causes, incidence, and risk factors
Persons with this disease have blood cells that are missing a gene called PIG-A. This gene allows a substance called glycosyl-phosphatidylinositol (GPI) to help certain proteins stick to cells.
Without PIG-A, important proteins cannot connect to the cell surface and protect the cell from substances in the blood called...
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Snoring Information
Source: ADAM Encyclopedia
Waking at night short of breath; Paroxysmal nocturnal dyspnea; PND; Difficulty breathing while lying down; OrthopneaReferencesHess OM, Carroll JD.... Read more »
Serum hemoglobin
Source: ADAM Encyclopedia
Blood hemoglobin; Serum hemoglobin Normal Values Females 12.315.3 g/dL Males 14.017.5 g/dL Note: g/dL = grams per... Read more »
Breathing difficulty
Source: ADAM Encyclopedia
Breathing difficulty while lying down is an abnormal condition in which a person must keep the head raised (by sitting or standing) to be able to... Read more »
Hemoglobin
Source: ADAM Encyclopedia
Hgb; HbNormal ValuesNormal results vary, but in general are:Male: 13.8 to 17.2 gm/dLFemale: 12.1 to 15.1 gm/dLNote: gm/dL = grams per deciliterNote:... Read more »
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