African trypanosomiasis
Prevention
Pentamidine injections protect against T. gambiense, but not against T. rhodesiense. Because it is a toxic drug, usuing it for prevention is not recommended.
Insect control measures can help prevent the spread of sleeping sickness in high-risk areas.
References
Kirchoff LV. Agents of African trypanosomiasis (sleeping sickness). In: Mandell GL, Bennett JE, Dolan R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Orlando, FL: Saunders Elsevier;2009:chap 278.
Quinn TC. African trypanosomiasis (sleeping sickness). In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 367.
Review Date: 12/07/2010
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of
General Medicine, Department of Medicine, University of Washington
School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in
Medicine, Harvard Medical School, Assistant in Medicine, Division
of Infectious Disease, Department of Medicine, Massachusetts
General Hospital. Also reviewed by David Zieve, MD, MHA, Medical
Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)

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