Generic Name: ZALEPLON - ORAL
Pronounced: (ZAL-e-plon)

Sonata Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur:

• sodium oxybate

If you are currently using the medication listed above, tell your doctor or pharmacist before starting zaleplon.

Tell your doctor of all prescription and nonprescription medication you may use, especially of:

• melatonin
• drugs affecting liver enzymes that remove zaleplon from your body (e.g., azole antifungals such as ketoconazole, cimetidine, rifamycins such as rifabutin/rifampin, certain anti-seizure medicines such as phenytoin, carbamazepine, phenobarbital)

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine, promethazine), anti-seizure drugs (e.g., levetiracetam), other drugs for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants (e.g., cyclobenzaprine, carisoprodol), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., thioridazine, risperidone, amitriptyline, trazodone).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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