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Tuesday, December 2, 2008

Diagnosis

(Page 4)

Other Causes of Persistent Fatigue. A number of conditions can cause persistent fatigue and should be ruled out:

  • Obstructive sleep apnea. This is a major sleep disorder that causes fatigue and afternoon sleepiness and must be ruled out before a diagnosis of narcolepsy can be established. (A person may also suffer sleep apnea and narcolepsy at the same time.)
  • Chronic fatigue syndrome
  • Head trauma
  • Infectious mononucleosis
Infectious mononucleosis
Swollen lymph nodes, sore throat, fatigue and headache are some of the symptoms of mononucleosis, which is caused by the Epstein-Barr virus. It is generally self-limiting and most patients can recover in 4 to 6 weeks without medications.
  • Guillain-Barre syndrome
  • Hepatitis
  • Atypical pneumonia, particularly those involving echoviruses

Other Causes of Sleep Paralysis. Sleep paralysis may be triggered by certain conditions, such as:

  • Irregular sleep habits
  • Sleep deprivation
  • Shift work
  • Jet lag
  • Psychologic stress

These conditions may also worsen sleep paralysis in narcolepsy. Narcolepsy sleep paralysis usually occurs at the onset of sleep and is chronic.



Review Date: 07/13/2006
Reviewed By: Harvey Simon, M.D., Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital

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