Premenstrual Syndrome (PMS)

For very severe symptoms, or when other medications fail, your doctor may prescribe a medication that causes the ovaries to stop producing estrogen so that ovulation stops. Danocrine (Danazol) is a synthetic androgen that suppresses the hormones in the brain that trigger ovulation. Gonadotropin-releasing hormone (GRNH) agonists, such as leuprolide (Lupron), create a temporary menopausal state by suppressing hormones in the brain that control the production of ovarian hormones and ovulation. These medications can be used only for short periods of time. They commonly lead to hot flashes and other symptoms of menopause. If therapy needs to continue for more than six months, you will also have to take estrogen to prevent bone loss. Whether your symptoms are mild or severe, it always helps to have your family's understanding and support while you are being treated for PMS. For this reason, your doctor will encourage you to speak frankly with family members about your symptoms and your PMS treatment.