2/11/08 #10 - Sublingual magnesium as a Migraine abortive?

Health Professional

Full Question:

I heard that the same magnesium tablets that I take for Migraine prevention can be used under the tongue as a Migraine abortive. Is this accurate? Laura.


Dear Laura;

Sorry, but no, this is not accurate. Here's why...

  1. Trying that form of magnesium sublingually is pointless because it will not absorb via the sublingual mucosa.
  2. It's not going to absorb until it reaches the GI tract, and even then, the absorption rate will not abort a Migraine attack.
  3. The only form of magnesium that has been show to be effective acutely (for aborting a Migraine) is magnesium sulfate via IV infusion.

Based on what we know about the bioavailability and absorption rate of magnesium and its pharmacokinetics, if this has worked for someone, it was certainly the result of the placebo effect.

Good luck,
John Claude Krusz and Teri Robert

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