7/9/07 #10 - 5-HTP? Relpax better than Zomig?

Health Professional

Full Question:

I have been getting migraines for 25 years now. I am on Inderal 40 mg a day three times a day for prophylaxis and Zomig for migraines. Is 5-HTP something I should avoid using or could it help. I am confused as to whether it is an serotonin agonist or a receptor. I usually get migraines three times a month. Could Relpax work better for me than the Zomig? Thank you for your help. Sandy.


Dear Sandy;

5-HTP is neither a receptor nor an agonist. It's an amino acid produced by the human body from the essential amino acid L-tryptophan (LT), which is found in dietary proteins. It's clinical value is in it's ability to increase production of serotonin 5-HPT should not be used by those of us who take any of the triptans, SSRI antidepressants, or some other medications.

5-HTP is a potentially valuable dietary supplement that promotes the body's production of serotonin. It's important, however, to treat such supplements as you would any other drug and consult your doctor before trying them. As for Zomig and Relpax, certainly one could work better for you than the others. Individual Migraineurs sometimes need to try a few different triptans before finding the one that works best for them.

Good luck,
John Claude Krusz and Teri Robert

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