Alzheimer’s development stopped in mice
In a successful trial with mice, a research team from the University of California-San Diego was able to use a set of compounds to stop the production of the amyloid proteins associated with the development of Alzheimer's disease.
The researchers tested their compounds on mice that had been engineered to produce large amounts of amyloid proteins. Compared to untreated mice, researchers found that mice who were treated for two weeks showed a 50 percent reduction in amyloid plaque buildup.
Researchers say that the compounds are able to block the amyloid proteins in a new way which may in theory, “stop Alzheimer’s in its tracks.” They noted that because it only targets the amyloid precursor protein, that there may be very few side effects. If the compound is successful in human trials, researchers added that it may be used for those at high risk for Alzheimer’s as treatment before signs of dementia appear. The findings were published in _PLOS ONE. _