Alzheimer's Disease Drugs Coming in Next Decade
Experts say that drugs to help patients with Alzheimer’s disease could be available within the next decade.
“There are still a number of late-stage trials in progress,” said Heather Snyder, senior director of medical and scientific operations at the Alzheimer’s Association, CNN reported. “2025 is a realistic target in terms of where we are with the science. … We’re not off-track at this point in time.”
With 24 drug candidates currently being tested on a large number of people, Snyder believes a few of these trial drugs will be successful in treating Alzheimer’s.
According to the Alzheimer’s Disease International, there were an estimated 46.8 million in the world living with dementia in 2015. That number is expected to double every 20 years and reach 74.7 million by 2030.
Biogen is one of the drug manufacturers working on trial drugs that will combat the disease that affects millions of people.
CNN reports that the drug developer announced promising results for one of its three trials at the Clinical Trials on Alzheimer’s Disease conference in San Diego last week.
Biogen’s aducanumab targets certain proteins which form plaque between nerve cells in the brain, which destroys surrounds cells. This plaque can appear in the brain up to 20 years before Alzheimer’s symptoms even begin, CNN reports.
When the drug successfully reduced existing plagues on Biogen’s trial patients, experts saw a slowing of mental decline after one year.
Another approach is to stop plaque from forming in the first place, using BACE inhibitors. However, experts believe BACE inhibitors are being given to patients too late.
Sourced from CNN