An Antioxidant for Bipolar Disorder?

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Coenzyme Q10, also called CoQ10, can effectively treat bipolar depression, according to results of a small study published in the Journal of Clinical Psychopharmacology.

This study supports additional research showing that CoQ10, which occurs naturally in the body and is also available as a supplement, eases depression symptoms in people with medical conditions like multiple sclerosis (MS) or breast cancer and enhances feelings of well-being and energy levels in seniors and veterans. CoQ10 works as an antioxidant — that is, it helps protect cells from damage — and is available in doses ranging from 50 to 1,200 milligrams.

The study involved 89 people with moderate bipolar depression divided into two groups, 20 of whom dropped out before study completion. In addition to their usual treatments, which involved mood stabilizers or antidepressants, one group was given 200 mg/day of CoQ10 and the other was given a placebo. During the first four weeks of the study, both groups experienced a similar improvement in depression symptoms, but after eight weeks, the group given CoQ10 experienced significantly more improvement. According to the researchers, higher doses of the supplement might produce an even better response.

Sourced from: Journal of Clinical Psychopharmacology