"Bath salt" drugs may be more addictive than meth
"Bath Salts"--a synthetic drug made from the compound methylenedioxypyrovalerone (MDPV)--may be more addictive than methamphetamine, concludes a study published in the journal Neuropharmacology. The study found that the rats worked much harder to get another dose of MDPV than they did to get an additional dose of meth.
Meth is known to be one of the more addictive drugs. But, the rats pressed a lever an average of 600 times to get MDPV, and pressed the lever only 60 times to get meth.
The study found that the rats responded to MDPV as a classical stimulant - becoming highly active, licking themselves repeatedly. biting and sniffing. The dose of MDPV that the rats started responding to was much lower than the meth dosage, suggesting that MDPV is more potent and effective at changing the rat's behavior. The rats learned that pressing a lever would give them another dose of the drug. When the supply was cut, they continued to press the lever, and sometimes they were rewarded with more.
Researchers say that while rodent studies don't always translate to humans, drugs that are readily self-administered by rats are usually compounds that humans are more likely to abuse.