A Blood Test to Rule Out Breast Cancer Despite Tissue Density


Nearly half of all women in the United States have dense breast tissue, increasing their breast cancer risk and decreasing the reliability of imaging tests used to detect the disease. Now, a study published in PLOS ONE suggests a biomarker blood test – called Videssa Breast – can rule out breast cancer in women with both dense and non-dense breast tissue with 99 percent accuracy.

The study was conducted by Provista Diagnostics, Inc., a private company focused on developing blood-based diagnostic, prognostic, and monitoring tests in the field of women’s cancers. Researchers evaluated Videssa Breast in 545 women between 25 and 50 with abnormal or difficult-to-interpret imaging. They found that the negative predictive value – the probability that subjects with a negative screening test truly do not have breast cancer – was 99.1 percent in women with dense breast tissue and 99.3 percent in women with non-dense tissue. This test is currently available for patients with abnormal imaging findings.

Sourced from PLOS One