**Can Coffee Reduce Obesity and Diabetes?
**** Obesity-Related Insulin Resistance
Obesity may come with co-morbid disorders such as Type 2 diabetes and heart disease. The link between them is a major risk factor for both illnesses:
obesity-related insulin resistance.
People who are obese develop a resistance to insulin on the cellular level. Insulin becomes less-able to restrain glucose output from the liver and to advance glucose uptake in fat and muscle. Increasing or decreasing insulin sensitivty has been shown to strongly correlate with gaining or losing weight in both animal and human studies.
Insulin resistance is a key concern because it is a major component of Type 2 diabetes, an illness that has reached epidemic proportions in the United States. Six percent of the U.S. adult population has been diagnosed with diabetes and another forty-one million are pre-diabetic. _Read: Diabetes Type 3: The Triad of Obesity, Diabetes, and Alzheimer's Disease
Coffee for Reducing Insulin Resistance
Given these concerns, some bright news has come from researchers at the University of Georgia. Scientists have found that chlorogenic acid or** CGA**, a chemical compound commonly found in coffee,** significantly reduces insulin resistance** and build up of fat in livers of mice who were fed a high-fat diet. The CGA compound is also found in fruits and vegetables such as apples, pears, tomatoes and blueberries.
In order to test the effects of CGA, researchers fed a group of mice a high-fat diet for 15 weeks and also injected them a CGA solution two times per week.
proved to be effective in preventing weight gain
as well as helping to maintain blood sugar levels and a healthy liver.
A study conducted by Nestle scientists in collaboration with Lausanne University Hospital and the University of Bern, Switzerland came to the same conclusion as the University of Georgia researchers.
CGA reduces inflammation, and there is substantial evidence suggesting that obesity-related diseases are caused by chronic inflammation. The hope is that if inflammation is controlled then some of the effects of weight gain can be as well.
Coffee May Reduce Risk for Diabetes
Prior studies have shown a steady correlation between coffee consumption and a lower rate of type 2 diabetes. This
has also been confirmed by a published meta-analysis that reviewed thirty-one human studies.
Harvard researchers analyzed data on 126,000 people and found that people who drank one to three cups of caffeinated coffee per day** can reduce the risk for diabetes by 10 percent** compared to people who do not drink coffee. Six cups per day reduced diabetes in men by 54 percent and diabetes in women by 30 percent compared to those who did not drink coffee.
The authors of the study point out that CGA will not cure obesity on its own. Diet and exercise remain critical components. It also was noted that the study mice received dosages of CGA that are much higher than a person would absorb by drinking coffee or eating a diet that is plentiful in fruits and vegetables. Read: Cure Obesity by Organizing Your Food
Other Study Finds Too Much Coffee May Cause Weight GainAustralian researchers found that** over-consumption of CGA**, about 5-cups of coffee a day,** may lead to weight gain and increase insulin-resistance**. The researchers claim that a moderate intake of coffee, up to three to four cups a day, seems to decrease the risk of developing diseases such as heart disease and type 2 diabetes. The ** study** was published in the Journal of Agricultural and Food Chemistry.
Bottom LineMore research will be done to try to develop a CGA formulation geared for weight loss in humans. Until then, expensive over-the-counter supplements such as** Green Coffee Bean Extract** may be** more hype than hope** as a viable weight loss solution.
Read: The Skinny on Weight Loss Medications
See Also: Coffee drinkers have "cleaner" arteries (Daily Dose)
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**** Genes and Development**
Nestle Research Center