Can I Take Migraine Drugs During Medication Overuse?

Health Professional
Medically Reviewed

Question: I am about to start withdrawal from zolmitriptan for medication overuse headache. Can I take any other pain relief whilst stopping Zomig such as Paramax (acetaminophen/metoclopramide) or aspirin to ease the pain or an antiemetic such as Buccastem (prochlorperazine) or do I have to just stick it out? Thanks, Hazel.

Answer: Dear Hazel; Nobody online can tell you what you can take because there are additional pieces to the puzzle that must be considered to answer it safely. All the medications you take, including over-the-counter medications and supplements, must be considered as well as your medical history.

That said, we can give you general information that you can discuss with your doctor. When working to get out of a medication overuse situation, in general, patients:

  • Stop taking the medication that has caused the problem, for a period of time determined by their doctor.
  • Avoid other medications in the same family as the medication that has caused the problem.
  • May use other migraine abortive medications, but should use them no more than two or three days per week.
  • May use other medications such as antiemetics for symptomatic relief.

Hazel, your doctor may tell you that you may use the Paramax or aspirin during this time, but please keep in mind that they can cause medication overuse headache, so the number of days per week that you use them should be limited.

We hope this information helps you discuss your options with your doctor.

Thank you for your question, Dave Watson and Teri Robert

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See more helpful articles:

How Can I Avoid Overusing Migraine and Headache Medications?

Medication Overuse Headache: When the Remedy Backfires

How to Treat Migraines Without Overusing Medications