Depression Can Take a Toll on Your Body

Depression clearly has a harmful effect on physical health, although the biological reasons for the link between body and mind are unclear. It may be that depression affects health because people develop a fatalistic attitude and stop taking care of themselves.

Whatever the reasons, over the past 20 years it has become evident that a depressed mood after a heart attack is much more than an “under-standable emotional reaction” to a stressful, life-changing event——it is profoundly dangerous, raising a person’s chances of having a second, fatal heart attack. One recent study found that people with depression who suffer a heart attack are at increased risk for complications while still in the hospital.

Researchers have also studied the flip side of the equation—the question of whether someone who is depressed is at increased risk for developing coronary heart disease down the line. Prospective studies show that people who had no coronary heart disease but were depressed when the studies began were more likely to develop or die of heart disease.

A Norwegian study found that people with significant depression had a higher risk of dying of most major causes of death, even after adjusting for age, medical conditions, and physical complaints. Depression also aggravates chronic illnesses such as diabetes, arthritis, back problems, and asthma, leading to more disability and doctor visits.

However, a study published in 2014 in Psychosomatic Medicine reported that early treatment of depression can greatly reduce the risk of heart attack and strokes. The researchers noted that the risk reduction was comparable to major cardiovascular disease prevention strategies like quitting smoking and exercising.

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HealthAfter50 was published by the University of California, Berkeley, School of Public Health, providing up-to-date, evidence-based research and expert advice on the prevention, diagnosis, and treatment of a wide range of health conditions affecting adults in middle age and beyond. It was previously part of Remedy Health Media's network of digital and print publications, which also include HealthCentral; HIV/AIDS resources The Body and The Body Pro; the UC Berkeley Wellness Letter; and the Berkeley Wellness website. All content from HA50 merged into in 2018.