Does Hydrocodone Cause Water Retention?

Question

Asked by detest

Does Hydrocodone Cause Water Retention?

I'm on alprazolam and hydrocodone and my lower legs/feet seem to be swelling some. Is this normal? Am I dying???

Answer

The ibuprofen in the hydrocodone could be causing edema or swelling. Edema, is not an uncommon symptom actually - many things can cause it. (Even the heat of summer can cause some edema in some people). Lower leg swelling is definitely not a symptom of imminent death - it happens fairly frequently in the population - but it should get checked out. The best thing to do is to tell your doctor about your new symptom and get it checked out.